Mouse GRP170 Monoclonal Antibody | anti-GRP170 antibody
GRP170 Monoclonal Antibody
Applications
ELISA, Immunoblot, Western Blot
Synonyms
GRP170; Monoclonal Antibody; GRP170 Monoclonal Antibody; Anti-Grp170; anti-GRP170 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2b
Form/Format
100ug in PBS (1mg/ml), pH 7.4, 0.1% sodium azide, 50% glycerol. Purified by Protein G affinity chromatography.
Applicable Applications for anti-GRP170 antibody
ELISA (EIA), Immunoblot (IB)
Application Notes
ELISA: Confirmed with antibody (1-10ug/ml) binding to Grp170 at 5ug/ml on the solid phase.
Immunoblotting: confirmed with antibody at 1.0-2.0ug/ml. A band of 170kDa is detected.
Immunoblotting: confirmed with antibody at 1.0-2.0ug/ml. A band of 170kDa is detected.
Antigen
Synthetic peptide sequence derived from human Grp170 (accession no. NP_006389.3)
Positive Control
HEK293 cell lysate.
Dilution Instructions
Dilute in PBS or medium that is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
Related Product Information for anti-GRP170 antibody
Grp170 is a major chaperone/stress protein resident in the ER. It is distantly related in sequence to both hsp110 and hsp70 families, but represents the Grp170 stress protein family. Studies have suggested that Grp170 is an important element of the protein processing machinery of the ER. Unlike Hsp110 and Hsp70, Grp170 has two distinct chaperoning domains; a classic beta-sheet peptide binding domain, with some COOH-terminal sequence, and a COOH-terminal alpha-helical domain. Like other members of the Hsp70 superfamily, Grp170 can elicit anti-tumor immune responses most likely by chaperoning antigenic peptide and binding to receptor(s) on antigen-presenting cells (APC).
Product Categories/Family for anti-GRP170 antibody
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Product Notes
The GRP170 (Catalog #AAA190646) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's GRP170 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoblot (IB). ELISA: Confirmed with antibody (1-10ug/ml) binding to Grp170 at 5ug/ml on the solid phase. Immunoblotting: confirmed with antibody at 1.0-2.0ug/ml. A band of 170kDa is detected. Researchers should empirically determine the suitability of the GRP170 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GRP170, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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