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Mouse anti-Human Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2D (GRIN2D) Monoclonal Antibody | anti-GRIN2D antibody

HRP-Linked Monoclonal Antibody to Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2D (GRIN2D)

Gene Names
GRIN2D; EB11; NR2D; GluN2D; NMDAR2D
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation
Purity
Protein A + Protein G affinity chromatography
Synonyms
Glutamate Receptor; Ionotropic; N-Methyl-D-Aspartate 2D (GRIN2D); Monoclonal Antibody; HRP-Linked Monoclonal Antibody to Glutamate Receptor; GRIN2D/Glutamate Receptor; N-Methyl-D-Aspartate 2D; EB11; NMDAR2D; NR2D; N-Methyl-d-Aspartate Receptor Subunit 2D; Glutamate [NMDA] receptor subunit epsilon-4; anti-GRIN2D antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1 Kappa
Clone Number
C6
Specificity
The antibody is a Mouse monoclonal antibody Antibody raised against Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2D (GRIN2D). It has been selected for its ability to recognize GRIN2D in immunohistochemical staining and western blotting.
Purity/Purification
Protein A + Protein G affinity chromatography
Form/Format
Liquid; PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Concentration
>=1mg/mL (Please refer to the vial label for the specific concentration.) (varies by lot)
Applicable Applications for anti-GRIN2D antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes
WB: 0.5-2ug/mL
IHC: 5-20ug/mL
ICC: 5-20ug/mL
Immunogen
Recombinant proteins/RP
Sequence of Immunogen
Phe28~Ala584 (Accession # O15399), with N-terminal His Tag
Organism Species
Human
Conjugation
HRP
Preparation and Storage
Store at 4 degree C for frequent use, -20 degree C for 24 months
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Product Categories/Family for anti-GRIN2D antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
143,752 Da
NCBI Official Full Name
glutamate receptor ionotropic, NMDA 2D
NCBI Official Synonym Full Names
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
NCBI Official Symbol
GRIN2D
NCBI Official Synonym Symbols
EB11; NR2D; GluN2D; NMDAR2D
NCBI Protein Information
glutamate receptor ionotropic, NMDA 2D; estrogen receptor binding CpG island; N-methyl D-aspartate receptor subtype 2D; N-methyl-d-aspartate receptor subunit 2D; glutamate [NMDA] receptor subunit epsilon-4
UniProt Protein Name
Glutamate receptor ionotropic, NMDA 2D
UniProt Gene Name
GRIN2D
UniProt Synonym Gene Names
GluN2D; NMDAR2D; GluN2D; NMDAR2D; NR2D
UniProt Entry Name
NMDE4_HUMAN

NCBI Description

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by RefSeq, Mar 2010]

Uniprot Description

NMDAR2D: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2D/GRIN2D subfamily.

Protein type: Membrane protein, multi-pass; Channel, ligand-gated; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: postsynaptic membrane; dendrite; plasma membrane; cell junction; N-methyl-D-aspartate selective glutamate receptor complex

Molecular Function: protein binding; extracellular-glutamate-gated ion channel activity; N-methyl-D-aspartate selective glutamate receptor activity

Biological Process: synaptic transmission; synaptic transmission, glutamatergic; startle response; adult locomotory behavior; ionotropic glutamate receptor signaling pathway; regulation of sensory perception of pain; signal transduction

Research Articles on GRIN2D

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Product Notes

The GRIN2D grin2d (Catalog #AAA2126461) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The HRP-Linked Monoclonal Antibody to Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2D (GRIN2D) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2D (GRIN2D) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP). WB: 0.5-2ug/mL IHC: 5-20ug/mL ICC: 5-20ug/mL. Researchers should empirically determine the suitability of the GRIN2D grin2d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2D (GRIN2D), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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