Mouse anti-Human Ganglioside GD3 Monoclonal Antibody | anti-siat8a antibody
Ganglioside GD3
Gene Names
siat8a; St8sia1
Reactivity
Human
Applications
Flow Cytometry, Immunofluorescence, Immunohistochemistry
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
Ganglioside GD3; Monoclonal Antibody; Anti -Ganglioside GD3; anti-siat8a antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG3
Clone Number
2Q631
Specificity
Recognizes human GD3 ganglioside1. Does not crossreact with other gangliosides purified from neuroblastoma or melanoma cells.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.6, 0.09% sodium azide.
Concentration
1 mg/mL (varies by lot)
Applicable Applications for anti-siat8a antibody
Suitable for use in Flow Cytometry, Immunofluorescence and Immunohistochemistry. Other applications not tested.
Application Notes
Flow Cytometry: 1-2ug/ml per 10e6 cells cells. Lysis of GD3 positive (melanoma) cells in presence of complement.
Immunohistochemistry: Frozen tissue sections
Immunofluorescence: Cells in culture
Optimal dilutions to be determined by the researcher.
Immunohistochemistry: Frozen tissue sections
Immunofluorescence: Cells in culture
Optimal dilutions to be determined by the researcher.
Immunogen
FM9 melanoma cells
Preparation and Storage
May be stored at 4°C. For long term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the orinal vial prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-siat8a antibody
GD3 has been identified as tumor-associated antigens expressed on the surface of neuroectoderm-derived tumors (melanoma, neuroblastoma and glioma) and T-cell leukemia. Gangliosides (sialic acid-containing glycosphingolipids) are normal membrane constituents and highly expressed in the vertebral central nervous system.
Product Categories/Family for anti-siat8a antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
38,191 Da
NCBI Official Full Name
ganglioside GD3 synthase
NCBI Official Symbol
siat8a
NCBI Official Synonym Symbols
St8sia1
NCBI Protein Information
alpha-2,8-sialyltransferase 1
UniProt Protein Name
Ganglioside GD3 synthase
UniProt Gene Name
siat8a
UniProt Entry Name
Q5K022_ORYLA
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Product Notes
The siat8a siat8a (Catalog #AAA603896) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Ganglioside GD3 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Ganglioside GD3 can be used in a range of immunoassay formats including, but not limited to, Suitable for use in Flow Cytometry, Immunofluorescence and Immunohistochemistry. Other applications not tested. . Flow Cytometry: 1-2ug/ml per 10e6 cells cells. Lysis of GD3 positive (melanoma) cells in presence of complement. Immunohistochemistry: Frozen tissue sections Immunofluorescence: Cells in culture Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the siat8a siat8a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ganglioside GD3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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