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Western Blot (WB) (Western blot analysis using GABPA mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY GABPA cDNA (2).)

Mouse anti-Human, Mouse GABPA Monoclonal Antibody | anti-GABPA antibody

Anti-GABPA Mouse mAb

Gene Names
GABPA; NFT2; NRF2; NRF2A; E4TF1A; E4TF1-60; RCH04A07
Reactivity
Human, Mouse
Applications
Western Blot, Immunocytochemistry
Synonyms
GABPA; Monoclonal Antibody; Anti-GABPA Mouse mAb; NFT2; NRF2; anti-GABPA antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
8C1B10
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
293
Applicable Applications for anti-GABPA antibody
Western Blot (WB), Immunocytochemistry (ICC)
Immunogen
Purified recombinant fragment of human GABPA (aa120-190) expressed in E Coli.

Western Blot (WB)

(Western blot analysis using GABPA mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY GABPA cDNA (2).)

Western Blot (WB) (Western blot analysis using GABPA mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY GABPA cDNA (2).)

Western Blot (WB)

(Western blot analysis using GABPA mouse mAb against Hela (1), A549 (2), MCF-7 (3), NIH/3T3 (4) and SMMC-7721 (5) cell lysate.)

Western Blot (WB) (Western blot analysis using GABPA mouse mAb against Hela (1), A549 (2), MCF-7 (3), NIH/3T3 (4) and SMMC-7721 (5) cell lysate.)

Immunofluorescence (IF)

(Confocal immunofluorescence analysis of Hela cells using GABPA mouse mAb (green). Red)

Immunofluorescence (IF) (Confocal immunofluorescence analysis of Hela cells using GABPA mouse mAb (green). Red)
Related Product Information for anti-GABPA antibody
Entrez Summary: GABPA: GA binding protein transcription factor, alpha subunit 60kDa. It is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, it may play a role in the Down Syndrome phenotype.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
51
NCBI Official Full Name
GABPA
NCBI Official Synonym Full Names
GA binding protein transcription factor alpha subunit
NCBI Official Symbol
GABPA
NCBI Official Synonym Symbols
NFT2; NRF2; NRF2A; E4TF1A; E4TF1-60; RCH04A07
NCBI Protein Information
GA-binding protein alpha chain
UniProt Protein Name
GA-binding protein alpha chain
Protein Family
UniProt Gene Name
GABPA
UniProt Synonym Gene Names
E4TF1A; GABP subunit alpha

NCBI Description

This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2010]

Uniprot Description

GABPA: Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene. Belongs to the ETS family.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 21q21.3

Cellular Component: nuclear chromatin; nucleoplasm; nucleus

Molecular Function: DNA binding; protein binding; protein heterodimerization activity; transcription coactivator activity; transcription factor activity

Biological Process: cell differentiation; mitochondrion organization and biogenesis; positive regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter

Research Articles on GABPA

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Product Notes

The GABPA gabpa (Catalog #AAA475824) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-GABPA Mouse mAb reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GABPA can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the GABPA gabpa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GABPA, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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