Mouse anti-Human, Rat FXR Monoclonal Antibody | anti-fxr antibody
FXR (Farnesoid X-activated Receptor, HRR-1, BAR, RIP14, NR1H4)
Gene Names
fxr; fxr
Reactivity
Human, Rat
Applications
ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry
Purity
PurifiedPurified by ammonium sulfate precipitation.
Synonyms
FXR; Monoclonal Antibody; FXR (Farnesoid X-activated Receptor; HRR-1; BAR; RIP14; NR1H4); Anti -FXR (Farnesoid X-activated Receptor; anti-fxr antibody
Host
Mouse
Reactivity
Human, Rat
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
5L1
Specificity
Recognizes human FXR. Species Crossreactivity: rat
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Purified by ammonium sulfate precipitation.
Form/Format
Supplied as a liquid in PBS, 0.1% sodium azide.
Applicable Applications for anti-fxr antibody
ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
Application Notes
Suitable for use in ELISA, Western Blot, Immunoprecipitation and Immunohistochemistry.
Dilution: Direct ELISA: 0.2ug/ml
Western Blot: 1ug/ml
Immunohistochemistry: 20-40ug/ml
Dilution: Direct ELISA: 0.2ug/ml
Western Blot: 1ug/ml
Immunohistochemistry: 20-40ug/ml
Immunogen
Recombinant protein corresponding to aa2-126 from human FXR.
Hybridoma
Spleen cells of a BALB/c mouse immunized with recombinant human FXR and mouse myeloma cells (NS-1).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-fxr antibody
Farnesoid X-activated receptor (FXR, HRR-1, BAR, RIP14; NR1H4) is a member of the orphan nuclear receptor family. FXR is expressed in the liver, intestinal villi, renal tubes and adrenal cortex. FXR is a global regulator of bile acid metabolism. Two genes, cholesterol 7a-hydroxylase (CYP7A1) and IBABP (ileal bile acid binding protein), which are implicated in bile acid biosynthesis and recycling, respectively, are target genes of FXR. FXR is shown to be transcriptionally activated by farnesol metabolites such as farnesol itself and juvenile hormone III. FXR binds to DNA only as a heterodimer with RXR.
Product Categories/Family for anti-fxr antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
3,844 Da
NCBI Official Full Name
FXR
NCBI Official Synonym Full Names
farnesoid X-activated receptor
NCBI Official Symbol
fxr
NCBI Official Synonym Symbols
fxr
NCBI Protein Information
farnesoid X-activated receptor
UniProt Protein Name
FXR
UniProt Gene Name
fxr
UniProt Entry Name
O42540_DANRE
Similar Products
Product Notes
The fxr fxr (Catalog #AAA603991) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The FXR (Farnesoid X-activated Receptor, HRR-1, BAR, RIP14, NR1H4) reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FXR can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC). Suitable for use in ELISA, Western Blot, Immunoprecipitation and Immunohistochemistry. Dilution: Direct ELISA: 0.2ug/ml Western Blot: 1ug/ml Immunohistochemistry: 20-40ug/ml. Researchers should empirically determine the suitability of the fxr fxr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FXR, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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