Mouse anti-Human FUCA1 Monoclonal Antibody | anti-FUCA1 antibody

FUCA1 (Alpha-L-fucosidase 1, Alpha-L-fucosidase I, Alpha-L-fucoside Fucohydrolase 1, FUCA, Nbla10230, Tissue alpha-L-fucosidase) (FITC)

Cat. Num. AAA6147279

• Gene Names: FUCA1; FUCA
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: FUCA1; Monoclonal Antibody; FUCA1 (Alpha-L-fucosidase 1; Alpha-L-fucosidase I; Alpha-L-fucoside Fucohydrolase 1; FUCA; Nbla10230; Tissue alpha-L-fucosidase) (FITC); anti-FUCA1 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2b,k
• Clone Number: 1D4
• Specificity: Recognizes human FUCA1.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).

• Applicable Applications for anti-FUCA1 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length recombinant corresponding to aa23-461 from human FUCA1 (AAH17338) with GST tag. MW of the GST tag alone is 26kD.
• Immunogen Sequence: VRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGVFIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEWADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK
• Conjugate: FITC
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot detection against Immunogen (74.03kD).)

Western Blot (WB)

(Western Blot analysis of FUCA1 expression in transfected 293T cell line by FUCA1 monoclonal antibody. Lane 1: FUCA1 transfected lysate (53.2kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-FUCA1 antibody

FUCA1 is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in this gene are associated with fucosidosis (FUCA1D), which is an autosomal recessive lysosomal storage disease. A pseudogene of this locus is present on chr 2.

Product Categories/Family for anti-FUCA1 antibody

Antibodies; Enzymes

NCBI and Uniprot Product Information

• NCBI GI #: 40226054
• NCBI GeneID: 2517
• Molecular Weight: 53,689 Da
• NCBI Official Full Name: Homo sapiens fucosidase, alpha-L- 1, tissue, mRNA
• NCBI Official Synonym Full Names: fucosidase, alpha-L- 1, tissue
• NCBI Official Symbol: FUCA1
• NCBI Official Synonym Symbols: FUCA
• NCBI Protein Information: tissue alpha-L-fucosidase
• Protein Family: Tissue alpha-L-fucosidase

NCBI Description

The protein encoded by this gene is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in this gene are associated with fucosidosis (FUCA1D), which is an autosomal recessive lysosomal storage disease. A pseudogene of this locus is present on chr 2.[provided by RefSeq, Oct 2009]