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Mouse anti-Human FSH beta Monoclonal Antibody | anti-FSH beta antibody

FSH beta antibody (HRP)

Gene Names
FSHB; HH24
Reactivity
Human
Applications
User optimized
Purity
FSH Beta antibody (HRP) was purified using a a proprietary chromatographic technique.
Synonyms
FSH beta; Monoclonal Antibody; FSH beta antibody (HRP); Monoclonal FSH beta; Anti-FSH beta; Follicle Stimulating Hormone beta; anti-FSH beta antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Clone Number
M605113-HRP
Specificity
Human
Purity/Purification
FSH Beta antibody (HRP) was purified using a a proprietary chromatographic technique.
Form/Format
Liquid in a stabilized protein buffer solution, pH 7.6, with Thimerosal added as preservative.
Sequence Length
129
Applicable Applications for anti-FSH beta antibody
User optimized
Biological Significance
Follicle-stimulating hormone (FSH) is a hormone found in humans and other animals. It is synthesized and secreted by gonadotrophs of the anterior pituitary gland. FSH regulates the development, growth, pubertal maturation, and reproductive processes of the body. FSH and Luteinizing hormone (LH) act synergistically in reproduction. The structure of FSH is similar to those of LH, TSH, and hCG. The protein dimer contains 2 polypeptide units, labeled alpha and beta subunits. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids. The beta subunits vary.
Tag/Conjugate
HRP
Affinity Constant
9 x 10^9 l/mol
Immunogen
FSH beta antibody (HRP) was raised in mouse using human FSH beta as the immunogen.
Preparation and Storage
Store at 4 degree C
Related Product Information for anti-FSH beta antibody
Mouse monoclonal FSH beta antibody (HRP)
Product Categories/Family for anti-FSH beta antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
14,700 Da
NCBI Official Full Name
follicle-stimulating hormone
NCBI Official Synonym Full Names
follicle stimulating hormone, beta polypeptide
NCBI Official Symbol
FSHB
NCBI Official Synonym Symbols
HH24
NCBI Protein Information
follitropin subunit beta
UniProt Protein Name
Follitropin subunit beta
UniProt Gene Name
FSHB
UniProt Synonym Gene Names
FSH-B; FSH-beta
UniProt Entry Name
FSHB_HUMAN

NCBI Description

The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

Uniprot Description

FSHB: Stimulates development of follicle and spermatogenesis in the reproductive organs. Defects in FSHB are a cause of isolated follicle- stimulating hormone deficiency (IFSHD). Selective follicle-stimulating hormone deficiency is an uncommon cause of infertility, producing amenorrhea and hypogonadism in women and oligo or azoospermia with normal testosterone levels in normally virilised men. Belongs to the glycoprotein hormones subunit beta family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 11p13

Cellular Component: cytoplasm; extracellular region

Molecular Function: follicle-stimulating hormone activity; protein binding; hormone activity

Biological Process: progesterone biosynthetic process; follicle-stimulating hormone signaling pathway; peptide hormone processing; female gamete generation; Sertoli cell proliferation; female pregnancy; signal transduction; regulation of osteoclast differentiation; cellular protein metabolic process; transforming growth factor beta receptor signaling pathway; positive regulation of cell proliferation; positive regulation of bone resorption; positive regulation of transcription from RNA polymerase II promoter; positive regulation of cell migration

Disease: Follicle-stimulating Hormone Deficiency, Isolated

Research Articles on FSH beta

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Product Notes

The FSH beta fshb (Catalog #AAA531066) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The FSH beta antibody (HRP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FSH beta can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the FSH beta fshb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FSH beta, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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