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Mouse FSH Monoclonal Antibody | anti-FSH BETA 2 antibody

MOUSE ANTI HUMAN FSH BETA 2

Applications
Immunohistochemistry, ELISA, Immunohistochemistry
Synonyms
FSH; Monoclonal Antibody; MOUSE ANTI HUMAN FSH BETA 2; anti-FSH BETA 2 antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
INN-hFSH-60
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1 mg/ml (varies by lot)
Sequence Length
129
Applicable Applications for anti-FSH BETA 2 antibody
Immunohistology Frozen, ELISA (EIA), Immunohistology Paraffin
Perservative Stabilisers
0.09% Sodium Azide
Preparation
Immunogen
Human FSH
Histology Positive Control Tissue
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Related Product Information for anti-FSH BETA 2 antibody
Mouse anti HumanFSH beta 2, clone INN-hFSH-60 is directed against the Beta 2 epitope of the Beta subunit of hFSH, INN-hFSH-60 shows strong reactions with hFSH and beta-hFSH, but no cross-reactivity with hTSH, hLH, hCG, alpha-hCG or alpha-hFSH. The recognition site is located near the alpha 1 binding site on the hFSH molecule. It is not compatible with other anti-hFSH-beta antibodies.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
14,700 Da
NCBI Official Full Name
follitropin subunit beta
NCBI Official Synonym Full Names
follicle stimulating hormone, beta polypeptide
NCBI Official Symbol
FSHB
NCBI Protein Information
follitropin subunit beta; FSH-B; FSH-beta; follicle-stimulating hormone beta subunit; follitropin beta chain; follitropin, beta chain
UniProt Protein Name
Follitropin subunit beta
UniProt Gene Name
FSHB
UniProt Synonym Gene Names
FSH-B; FSH-beta
UniProt Entry Name
FSHB_HUMAN

NCBI Description

The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

Uniprot Description

FSHB: Stimulates development of follicle and spermatogenesis in the reproductive organs. Defects in FSHB are a cause of isolated follicle- stimulating hormone deficiency (IFSHD). Selective follicle-stimulating hormone deficiency is an uncommon cause of infertility, producing amenorrhea and hypogonadism in women and oligo or azoospermia with normal testosterone levels in normally virilised men. Belongs to the glycoprotein hormones subunit beta family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 11p13

Cellular Component: cytoplasm; extracellular region

Molecular Function: follicle-stimulating hormone activity; protein binding; hormone activity

Biological Process: progesterone biosynthetic process; cellular protein metabolic process; regulation of osteoclast differentiation; follicle-stimulating hormone signaling pathway; transforming growth factor beta receptor signaling pathway; positive regulation of cell proliferation; peptide hormone processing; female gamete generation; positive regulation of bone resorption; Sertoli cell proliferation; positive regulation of transcription from RNA polymerase II promoter; female pregnancy; signal transduction; positive regulation of cell migration

Disease: Follicle-stimulating Hormone Deficiency, Isolated

Research Articles on FSH BETA 2

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Product Notes

The FSH BETA 2 fshb (Catalog #AAA212976) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's FSH can be used in a range of immunoassay formats including, but not limited to, Immunohistology Frozen, ELISA (EIA), Immunohistology Paraffin. Researchers should empirically determine the suitability of the FSH BETA 2 fshb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FSH, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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