Western Blot (WB)
(Western blot analysis of FOXA2 on HT-29 cells lysates using anti-FOXA2 antibody at 1/500 dilution.)
Rabbit anti-Human FOXA2 Monoclonal Antibody | anti-FOXA2 antibody
FOXA2 Antibody
Gene Names
FOXA2; HNF3B; TCF3B
Reactivity
Human
Applications
Western Blot, Immunocytochemistry, Immunofluorescence
Purity
ProA affinity purified
Synonyms
FOXA2; Monoclonal Antibody; FOXA2 Antibody; Forkhead box A2 antibody; Forkhead box protein A2 antibody; FOX A2 antibody; foxa2 antibody; FOXA2_HUMAN antibody; Hepatic nuclear factor 3 beta antibody; Hepatocyte nuclear factor 3 antibody; Hepatocyte nuclear factor 3 beta antibody; Hepatocyte nuclear factor 3-beta antibody; HNF 3B antibody; HNF-3-beta antibody; HNF-3B antibody; HNF3B antibody; MGC19807 antibody; TCF 3B antibody; TCF-3B antibody; TCF3B antibody; Transcription factor 3B antibody; anti-FOXA2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Clone Number
JM10-64
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-FOXA2 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes
WB: 1:1000-5000
ICC: 1:50-1:200
ICC: 1:50-1:200
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
Western Blot (WB)
(Western blot analysis of FOXA2 on HT-29 cells lysates using anti-FOXA2 antibody at 1/500 dilution.)
Western Blot (WB)
(Western blot analysis of FOXA2 on HT-29 cells lysates using anti-FOXA2 antibody at 1/500 dilution.)
Related Product Information for anti-FOXA2 antibody
Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally discribed as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
Product Categories/Family for anti-FOXA2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
457
NCBI Official Full Name
hepatocyte nuclear factor 3-beta isoform 1
NCBI Official Synonym Full Names
forkhead box A2
NCBI Official Symbol
FOXA2
NCBI Official Synonym Symbols
HNF3B; TCF3B
NCBI Protein Information
hepatocyte nuclear factor 3-beta; HNF-3B; TCF-3B; HNF-3-beta; forkhead box protein A2; transcription factor 3B; hepatic nuclear factor-3-beta; hepatocyte nuclear factor 3, beta
UniProt Protein Name
Hepatocyte nuclear factor 3-beta
Protein Family
UniProt Gene Name
FOXA2
UniProt Synonym Gene Names
HNF3B; TCF3B; HNF-3-beta; HNF-3B; TCF-3B
UniProt Entry Name
FOXA2_HUMAN
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Product Notes
The FOXA2 foxa2 (Catalog #AAA9436234) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FOXA2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FOXA2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF). WB: 1:1000-5000 ICC: 1:50-1:200. Researchers should empirically determine the suitability of the FOXA2 foxa2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FOXA2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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