Rat anti-Mouse Forssman antigen Monoclonal Antibody
Rat anti Forssman antigen
Reactivity
Mouse
Applications
Immunohistochemistry
Synonyms
Forssman antigen; Monoclonal Antibody; Rat anti Forssman antigen; anti-Forssman antigen antibody
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG
Clone Number
33B12
Specificity
Clone 33B12 and 117C9 detect overlapping epitopes on the Forssman glycolipid hapten (GalNA1- c3aG alNAcD1 -3GalaI-4GalB1-4GlcBl-lCer). Clone 33B12 reacts with the terminal sugar sequence GalNAcd-3GalNAc and is specific for Forssman antigen.
Form/Format
Each vial contains 100 ul 1 mg/ml purified monoclonal antibody in PBS containing 0.09% sodium azide.
Applicable Applications for anti-Forssman antigen antibody
Immunohistochemistry (IHC) (frozen)
Application Notes
33B12 is useful for immubohistochemistry on frozen sections. Optimal antibody dilution should be determined by titRation.
Source Note
The antibody 33B12 is a Rat anti-Forrsman glycosphingolipid (FGL) antibody derived by fusing Mouse myeloma cells with spleen cells from a Rat immunized with Mouse mammary tumors.
Preparation and Storage
Store at 4 degree C, or in small aliquots at -20 degree C.
Related Product Information for anti-Forssman antigen antibody
The Forssman glycolipid is a glycosylceramide possessing a neutral pentasaccharide head group, referred to as the Forssman antigen (Fa) and is a member of the globoseries glycolipid family. Fa has been identified in a number of mammals and exhibits heterogeneity with respect to developmental and cell-type expression among species. Some studies have reported the presence of the Fa in certain Human embryonic and tumor cells.The majority of Human individuals have undetectable levels of Fa.Gastric and colonic tumors from Fa-negative patients, however, contained relatively high levels of Fa. Moreover, compared with normal lung tissue, many lung cancers contained elevated levels of Fa. These observations arouse interest in Fa for a possible role as a Human tumor antigen.
Product Categories/Family for anti-Forssman antigen antibody
References
Sonnenberg A, van Balen P, Hengeveld T, Kolvenbag GJ, Van Hoeven RP, Hilgers J., Monoclonal antibodies detecting different epitopes on the Forssman glycolipid hapten. J Immunol. 1986 Aug 15;137(4):1264-9
Similar Products
Product Notes
The Forssman antigen (Catalog #AAA570195) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Rat anti Forssman antigen reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Forssman antigen can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) (frozen). 33B12 is useful for immubohistochemistry on frozen sections. Optimal antibody dilution should be determined by titRation. Researchers should empirically determine the suitability of the Forssman antigen for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Forssman antigen, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
