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Foot-and-mouth disease Monoclonal Antibody | anti-FMDV antibody

Monoclonal mouse anti-Foot-and-mouth disease (FMDV)

Applications
ELISA, Immunodiffusion
Purity
Protein G Chromatography
Synonyms
Foot-and-mouth disease; Monoclonal Antibody; Monoclonal mouse anti-Foot-and-mouth disease (FMDV); anti-FMDV antibody
Ordering
For Research Use Only!
Clonality
Monoclonal
Isotype
IgG2a for MAbs 2D2
Clone Number
2D2
Specificity
MAb 2D2 is specific for virulent serotype O1.
Purity/Purification
Protein G Chromatography
Form/Format
PBS, pH 7.4, 0.09 % sodium azide (NaN3)
Concentration
2.1 mg/ml (varies by lot)
Sequence Length
241
Applicable Applications for anti-FMDV antibody
ELISA (EIA), Immunodiffusion
Clone Note
Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with inactivate FMD virus (MAbs 2D2 and 3G8), or recombinant non-structural  protein of FMDV (MAbs 1G2 and 1H4).
Mabs
2D2
Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with inactivate FMD virus.
Preparation and Storage
Store at 4°C. (2-8°C allowed)

NCBI and Uniprot Product Information

NCBI GI #
NCBI Official Full Name
FMDV polyprotein, partial
UniProt Protein Name
Genome polyprotein
UniProt Gene Name
Lpro
UniProt Synonym Gene Names
P2A; P2B; P2C; P3A; P3B-1; P3B-2; P3B-3; P3C; P3D-POL
UniProt Entry Name
POLG_FMDVA

Uniprot Description

The leader protease autocatalytically cleaves itself from the polyprotein at the L/VP0 junction. It cleaves the host translation initiation factors EIF4G1 and EIF4G3, in order to shut down the capped cellular mRNA transcription. Increases translation driven by the viral internal ribosome entry site (IRES).

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Product Notes

The FMDV lpro (Catalog #AAA660114) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Foot-and-mouth disease can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunodiffusion. Researchers should empirically determine the suitability of the FMDV lpro for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Foot-and-mouth disease, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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