Rat anti-Mouse Flk-1 Monoclonal Antibody | anti-Flk-1 antibody
Anti-mouse Flk-1 Monoclonal Antibody
NCBI and Uniprot Product Information
Uniprot Description
VEGFR2: a receptor tyrosine kinase of the VEGFR family. High affinity receptor for VEGF and VEGF-C. Ligand binding induces autophosphorylation and activation. Activated receptor recruits proteins including Shc, GRB2, PI3K, Nck, SHP-1 and SHP-2. Plays a key role in vascular development and regulation of vascular permeability.
Protein type: EC 2.7.10.1; Kinase, protein; Membrane protein, integral; Protein kinase, TK; Protein kinase, tyrosine (receptor); TK group; VEGFR family
Chromosomal Location of Human Ortholog: 5 C3.3|5 40.23 cM
Cellular Component: cell junction; cell soma; cell surface; cytoplasm; early endosome; endoplasmic reticulum; endosome; external side of plasma membrane; Golgi apparatus; integral to plasma membrane; lipid raft; neuron projection; nucleus; plasma membrane
Molecular Function: growth factor binding; integrin binding; protein binding; protein-tyrosine kinase activity; vascular endothelial growth factor receptor activity
Biological Process: alveolus development; branching morphogenesis of a tube; calcium ion homeostasis; cell fate commitment; cell maturation; cell migration; cell migration during sprouting angiogenesis; elevation of cytosolic calcium ion concentration; embryonic hemopoiesis; endothelial cell differentiation; hemopoiesis; lung development; lymph vessel development; male gonad development; negative regulation of apoptosis; negative regulation of neuron apoptosis; neurite morphogenesis; ovarian follicle development; peptidyl-tyrosine phosphorylation; positive regulation of angiogenesis; positive regulation of BMP signaling pathway; positive regulation of calcium-mediated signaling; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of endothelial cell proliferation; positive regulation of epithelial cell proliferation; positive regulation of focal adhesion formation; positive regulation of long-term neuronal synaptic plasticity; positive regulation of macroautophagy; positive regulation of MAPKKK cascade; positive regulation of mesenchymal cell proliferation; positive regulation of mitochondrial depolarization; positive regulation of nitric-oxide synthase biosynthetic process; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of positive chemotaxis; positive regulation of protein amino acid phosphorylation; positive regulation of TOR signaling pathway; positive regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of vasodilation; post-embryonic camera-type eye morphogenesis; protein amino acid autophosphorylation; regulation of cell shape; regulation of endothelial cell differentiation; regulation of endothelial cell proliferation; response to drug; response to hypoxia; surfactant homeostasis; vascular endothelial growth factor receptor signaling pathway; vasculogenesis
Research Articles on Flk-1
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Product Notes
The Flk-1 kdr (Catalog #AAA418467) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti-mouse Flk-1 Monoclonal Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Flk-1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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