Mouse anti-Human FGFR3 Monoclonal Antibody | anti-FGFR3 antibody
Anti-FGFR3 Mouse mAb
Reactivity
Human
Applications
Western Blot
Synonyms
FGFR3; Monoclonal Antibody; Anti-FGFR3 Mouse mAb; anti-FGFR3 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
2H2C4
Form/Format
Subclonal supernatant.
Sequence Length
376
Applicable Applications for anti-FGFR3 antibody
Western Blot (WB)
Immunogen
Purified recombinant fragment of SARS-m protein expressed in E Coli.
Related Product Information for anti-FGFR3 antibody
Entrez Summary: This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
87.7
NCBI Official Full Name
FGFR3, partial
UniProt Protein Name
FGFR3
Protein Family
UniProt Gene Name
FGFR3
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Product Notes
The FGFR3 fgfr3 (Catalog #AAA476950) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-FGFR3 Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FGFR3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the FGFR3 fgfr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FGFR3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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