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Immunohistochemistry - Paraffin (IHC) (Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE))

Mouse anti-Human FCGR1A / CD64 Monoclonal Antibody | anti-FCGR1A / CD64 antibody

Anti-FCGR1A / CD64 Antibody (clone 1A8) IHC-plus

Gene Names
FCGR1A; CD64; FCRI; CD64A; IGFR1
Reactivity
Human
Applications
Immunohistochemistry, Immunofluorescence, Western Blot
Purity
Immunoaffinity purified
Synonyms
FCGR1A / CD64; Monoclonal Antibody; Anti-FCGR1A / CD64 Antibody (clone 1A8) IHC-plus; Mouse Monoclonal [clone 1A8] (IgG1) to Human FCGR1A / CD64; Human FCGR1A / CD64; CD64A; CD64 antigen; FCG1; FcgammaRIa; IGFR1; IgG Fc receptor I; Fc-gamma receptor I A1; Fc-gamma RIA; FCGR1; Fc gamma receptor; Fc-gamma RI; FCRI; anti-FCGR1A / CD64 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1A8
Specificity
Human FCGR1A / CD64
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
374
Applicable Applications for anti-FCGR1A / CD64 antibody
Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB)
Application Notes
IF (1:100)
IHC-P (10 ug/ml)
WB (1:2000)
Immunogen
FCGR1A / CD64 antibody was raised against full length human recombinant protein of human FCGR1A(NP_000557) produced in HEK293T cell.
Immunogen Description
Full length human recombinant protein of human FCGR1A(NP_000557) produced in HEK293T cell.
Immunogen Type
Recombinant protein
Target Species
Human
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.

Immunohistochemistry - Paraffin (IHC)

(Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry - Paraffin (IHC) (Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry - Paraffin (IHC)

(Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry - Paraffin (IHC) (Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunofluorescence (IF)

(Anti-FCGR1A mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FCGR1A.)

Immunofluorescence (IF) (Anti-FCGR1A mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FCGR1A.)

Western Blot (WB)

(HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FCGR1A (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FCGR1A.)

Western Blot (WB) (HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FCGR1A (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FCGR1A.)
Related Product Information for anti-FCGR1A / CD64 antibody
FCGR1A Antibody, CD64A Antibody, CD64 Antibody, CD64 antigen Antibody, FCG1 Antibody, FcgammaRIa Antibody, IGFR1 Antibody, IgG Fc receptor I Antibody, Fc-gamma receptor I A1 Antibody, Fc-gamma RIA Antibody, FCGR1 Antibody, Fc gamma receptor Antibody, Fc-gamma RI Antibody, FCRI Antibody Description: High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,795 Da
NCBI Official Full Name
high affinity immunoglobulin gamma Fc receptor I
NCBI Official Synonym Full Names
Fc fragment of IgG receptor Ia
NCBI Official Symbol
FCGR1A
NCBI Official Synonym Symbols
CD64; FCRI; CD64A; IGFR1
NCBI Protein Information
high affinity immunoglobulin gamma Fc receptor I
UniProt Protein Name
High affinity immunoglobulin gamma Fc receptor I
UniProt Gene Name
FCGR1A
UniProt Synonym Gene Names
FCG1; FCGR1; IGFR1; IgG Fc receptor I; FcRI; FcgammaRIa
UniProt Entry Name
FCGR1_HUMAN

NCBI Description

This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008]

Uniprot Description

FCGR1A: High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Belongs to the immunoglobulin superfamily. FCGR1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 1q21.2-q21.3

Cellular Component: early endosome membrane; integral to membrane; plasma membrane

Molecular Function: IgG binding; protein binding; receptor signaling protein activity

Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; antigen processing and presentation of peptide antigen via MHC class I; cytokine and chemokine mediated signaling pathway; immune response; innate immune response; phagocytosis, engulfment; regulation of immune response; signal transduction

Research Articles on FCGR1A / CD64

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Product Notes

The FCGR1A / CD64 fcgr1a (Catalog #AAA249249) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-FCGR1A / CD64 Antibody (clone 1A8) IHC-plus reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FCGR1A / CD64 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB). IF (1:100) IHC-P (10 ug/ml) WB (1:2000). Researchers should empirically determine the suitability of the FCGR1A / CD64 fcgr1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FCGR1A / CD64, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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