anti-Mouse FcepsilonRIalpha Monoclonal Antibody | anti-FcepsilonRIalpha antibody
Anti-Mouse FcepsilonRIalpha Monoclonal Antibody (PE Conjugated)
Gene Names
Fcer1a; FcERI; Fce1a; Fcr-5; fcepsilonri
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay
Synonyms
FcepsilonRIalpha; Monoclonal Antibody; Anti-Mouse FcepsilonRIalpha Monoclonal Antibody (PE Conjugated); High affinity immunoglobulin epsilon receptor subunit alpha; Fc-epsilon RI-alpha; FcERI; Fcer1a; anti-FcepsilonRIalpha antibody
Host
Armenian Hamster
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG
Clone Number
MAR-1
Form/Format
PBS with 0.05% Proclin300, 1% BSA
Sequence Length
250
Applicable Applications for anti-FcepsilonRIalpha antibody
Flow Cytometry (FC/FACS)
Conjugation
PE
Preparation and Storage
Store at 2-8 degree C and protect from prolonged exposure to light. Do not freeze.
Related Product Information for anti-FcepsilonRIalpha antibody
FcepsilonRIalpha is a transmembrane protein belonging to the Ig superfamily. FcepsilonRIalpha forms a tetrameric complex with one beta and two gamma-subunits. The FcepsilonRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcepsilonRIalpha, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcepsilonRIalpha subunit.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
high affinity immunoglobulin epsilon receptor subunit alpha
NCBI Official Synonym Full Names
Fc receptor, IgE, high affinity I, alpha polypeptide
NCBI Official Symbol
Fcer1a
NCBI Official Synonym Symbols
FcERI; Fce1a; Fcr-5; fcepsilonri
NCBI Protein Information
high affinity immunoglobulin epsilon receptor subunit alpha
UniProt Protein Name
High affinity immunoglobulin epsilon receptor subunit alpha
UniProt Gene Name
Fcer1a
UniProt Synonym Gene Names
Fce1a; FcERI
Uniprot Description
Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
Research Articles on FcepsilonRIalpha
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Product Notes
The FcepsilonRIalpha fcer1a (Catalog #AAA2559351) is an Antibody produced from Armenian Hamster and is intended for research purposes only. The product is available for immediate purchase. The Anti-Mouse FcepsilonRIalpha Monoclonal Antibody (PE Conjugated) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's FcepsilonRIalpha can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the FcepsilonRIalpha fcer1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FcepsilonRIalpha, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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