Mouse anti-Human Fatty Acid Binding Protein 2, Intestinal (FABP2) Monoclonal Antibody | anti-FABP2 antibody

HRP-Linked Monoclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2)

Cat. Num. AAA2115601

• Gene Names: FABP2; FABPI; I-FABP
• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation
• Purity: Protein A + Protein G Affinity Chromatography
• Synonyms: Fatty Acid Binding Protein 2; Intestinal (FABP2); Monoclonal Antibody; HRP-Linked Monoclonal Antibody to Fatty Acid Binding Protein 2; FABPI; IFABP; I-FABP; Intestinal-type fatty acid-binding protein; anti-FABP2 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1 Kappa
• Clone Number: C4
• Specificity: The antibody is a mouse monoclonal antibody raised against FABP2. It has been selected for its ability to recognize FABP2 in immunohistochemical staining and western blotting.
• Purity/Purification: Protein A + Protein G Affinity Chromatography
• Form/Format: Liquid; 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
• Concentration: 500ug/ml (varies by lot)
• Sequence: Met1~Asp132

• Applicable Applications for anti-FABP2 antibody: Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
• Immunogen Sequence: Met1~Asp132
• Cross Reactivity: Human
• Conjugation: HRP
• Preparation and Storage: Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.; Avoid repeated freeze/thaw cycles.; The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Product Categories/Family for anti-FABP2 antibody

Metabolic Pathway; Tumor Immunity; Endocrinology; Cardiovascular Biology

NCBI and Uniprot Product Information

• NCBI GI #: 119805
• NCBI GeneID: 2169
• UniProt Accession #: P12104; Q2NKJ1
• Molecular Weight: 132
• NCBI Official Full Name: Fatty acid-binding protein, intestinal
• NCBI Official Synonym Full Names: fatty acid binding protein 2, intestinal
• NCBI Official Symbol: FABP2
• NCBI Official Synonym Symbols: FABPI; I-FABP
• NCBI Protein Information: fatty acid-binding protein, intestinal; fatty acid-binding protein 2; intestinal-type fatty acid-binding protein
• UniProt Protein Name: Fatty acid-binding protein, intestinal
• Protein Family: Fatty acid-binding protein
• UniProt Gene Name: FABP2
• UniProt Synonym Gene Names: FABPI; I-FABP
• UniProt Entry Name: FABPI_HUMAN

NCBI Description

The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. [provided by RefSeq, Jul 2008]

Uniprot Description

FABP2: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Chromosomal Location of Human Ortholog: 4q28-q31

Cellular Component: cytoplasm

Molecular Function: transporter activity; fatty acid binding

Biological Process: transport; digestion