Mouse anti-Human Farnesyltransferase, alpha subunit Monoclonal Antibody | anti-Chro.60290 antibody
Farnesyltransferase, alpha subunit (FNTA)
Reactivity
Human
Applications
Western Blot
Purity
Affinity PurifiedPurified by Protein A.
Synonyms
Farnesyltransferase; alpha subunit; Monoclonal Antibody; alpha subunit (FNTA); Anti -Farnesyltransferase; subunit (FNTA); anti-Chro.60290 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
7i16
Specificity
Specific to the alpha subunit of farnesyl transferase.
Purity/Purification
Affinity Purified
Purified by Protein A.
Purified by Protein A.
Form/Format
Supplied as a liquid in PBS with 0.1% sodium azide.
Applicable Applications for anti-Chro.60290 antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Dilution: Western Blot: 1:1000
Dilution: Western Blot: 1:1000
Immunogen
Full length GST-farnesyltransferase, alpha subunit protein
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-Chro.60290 antibody
Farnesyltransferase is one of the three enzymes in the prenyltransferase group. Specifically, farnesyltransferase (FTase) adds a 15 carbon isoprenoid called a farnesyl group to proteins bearing a CaaX motif: a four amino acid sequence at the carboxyl terminus of a protein. Farnesyltransferase's targets include members of the Ras superfamily of small GTP binding proteins critical to cell cycle progression. For this reason, several FTase inhibitors are undergoing testing as anti-cancer agents. FTase inhibitors have also shown efficacy as anti-parasitic agents as well. FTase is also believed to play an important role in development of progeria and various forms of cancers.
Farnesyltransferase, posttranslationally modify proteins by adding an isoprenoid lipid called a farnesyl group to the carboxyl terminus of the target protein. This process, called farnesylation (more generally prenylation), causes farnesylated proteins to become membrane associated due to the hydrophobic nature of the farnesyl group. Most farnesylated proteins are involved in cellular signaling where membrane association is critical for function. [edit]Farnesyltransferase structure and function
Farnesyltransferase, posttranslationally modify proteins by adding an isoprenoid lipid called a farnesyl group to the carboxyl terminus of the target protein. This process, called farnesylation (more generally prenylation), causes farnesylated proteins to become membrane associated due to the hydrophobic nature of the farnesyl group. Most farnesylated proteins are involved in cellular signaling where membrane association is critical for function. [edit]Farnesyltransferase structure and function
Product Categories/Family for anti-Chro.60290 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
farnesyltransferase
NCBI Official Symbol
Chro.60290
NCBI Protein Information
farnesyltransferase
Similar Products
Product Notes
The Chro.60290 (Catalog #AAA601772) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Farnesyltransferase, alpha subunit (FNTA) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Farnesyltransferase, alpha subunit can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Dilution: Western Blot: 1:1000. Researchers should empirically determine the suitability of the Chro.60290 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Farnesyltransferase, alpha subunit, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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