Western Blot (WB)
(Western Blot: HeLa nuclear lysate was resolved by electrophoresis, transferred to nitrocellulose and probed with MBS605447 (1:5000 dilution). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates EZH2 (~98kD).)
Mouse anti-Human, Mouse EZH2 Monoclonal Antibody | anti-EZH2 antibody
EZH2 (Histone-lysine N-methyltransferase EZH2, Enhancer of Zeste Homolog 2, ENX-1, Lysine N-methyltransferase 6) (MaxLight 650)
Gene Names
EZH2; WVS; ENX1; EZH1; KMT6; WVS2; ENX-1; EZH2b; KMT6A
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Purified by Protein G Affinity Chromatography
Synonyms
EZH2; Monoclonal Antibody; EZH2 (Histone-lysine N-methyltransferase EZH2; Enhancer of Zeste Homolog 2; ENX-1; Lysine N-methyltransferase 6) (MaxLight 650); anti-EZH2 antibody
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
9H236
Specificity
Recognizes human EZH2 (~98kD). Species Crossreactivity: mouse
Purity/Purification
Purified by Protein G Affinity Chromatography
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.
Applicable Applications for anti-EZH2 antibody
Western Blot (WB)
Immunogen
Recombinant fusion protein of aa1-286 of human EZH2 tagged with MBP. Cellular Localization: Nucleus. (NP_004447.2)
Conjugate
MaxLight650
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Western Blot (WB)
(Western Blot: HeLa nuclear lysate was resolved by electrophoresis, transferred to nitrocellulose and probed with MBS605447 (1:5000 dilution). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates EZH2 (~98kD).)
Western Blot (WB)
(Western Blot: HeLa nuclear lysate was resolved by electrophoresis, transferred to nitrocellulose and probed with MBS605447 (1:5000 dilution). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates EZH2 (~98kD).)
Product Categories/Family for anti-EZH2 antibody
References
1. Bracken, A.P., et al., Genes Dev. 21(5): 525-530 (2007). 2. Bracken, A.P., et al., Genes Dev. 20: 1123-1136 (2006). 3. Pasini, D., et al., Mol. Cell. Biol. 27: 3769-3779 (2007). 4. Pasini, D., et al., Genes Dev. 22: 1345-1355 (2008).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
79,621 Da
NCBI Official Full Name
histone-lysine N-methyltransferase EZH2 isoform a
NCBI Official Synonym Full Names
enhancer of zeste 2 polycomb repressive complex 2 subunit
NCBI Official Symbol
EZH2
NCBI Official Synonym Symbols
WVS; ENX1; EZH1; KMT6; WVS2; ENX-1; EZH2b; KMT6A
NCBI Protein Information
histone-lysine N-methyltransferase EZH2; enhancer of zeste homolog 2; lysine N-methyltransferase 6
UniProt Protein Name
Histone-lysine N-methyltransferase EZH2
Protein Family
UniProt Gene Name
EZH2
UniProt Synonym Gene Names
KMT6
UniProt Entry Name
EZH2_HUMAN
NCBI Description
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
Research Articles on EZH2
Similar Products
Product Notes
The EZH2 ezh2 (Catalog #AAA6246716) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The EZH2 (Histone-lysine N-methyltransferase EZH2, Enhancer of Zeste Homolog 2, ENX-1, Lysine N-methyltransferase 6) (MaxLight 650) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's EZH2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the EZH2 ezh2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EZH2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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