Mouse ERp31 Monoclonal Antibody | anti-ERp31 antibody

Anti-ERp31 Antibody

Cat. Num. AAA415172

• Gene Names: ERP29; ERp28; ERp31; PDIA9; PDI-DB; C12orf8; HEL-S-107
• Applications: ELISA, Western Blot
• Purity: Affinity purified
• Synonyms: ERp31; Monoclonal Antibody; Anti-ERp31 Antibody; anti-ERp31 antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Specificity: Anti-ERp31 recognizes ERp31 expression in MCF-7 whole cell lysate.
• Purity/Purification: Affinity purified
• Form/Format: Liquid
• Concentration: 100ug/100ul (varies by lot)
• Sequence Length: 1333

• Applicable Applications for anti-ERp31 antibody: ELISA (EIA), Western Blot (WB-Ce)
• Application Notes: WB: 1:1000 analysis of ERp31 expression in MCF-7 whole cell lysate with Anti-ERp31
• Raised In: Purified mouse monoclonal antibody generated using E.coli expressed recombinant protein ERp31 as immunogen.
• Storage Buffer: citrate-tris-HCl buffer pH7.0 with 0.02% Proclin 300.
• Immunogen: Recombinant protein corresponding to fragment (aa/33-261) ERp31.
• Preparation and Storage: This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Testing Data

References

None

NCBI and Uniprot Product Information

• NCBI GI #: 77628150
• NCBI GeneID: 10961
• NCBI Accession #: NP_001029197.1
• NCBI GenBank Nucleotide #: NM_001034025
• Molecular Weight: 5,477 Da
• NCBI Official Full Name: Homo sapiens endoplasmic reticulum protein 29 (ERP29), transcript variant 2, mRNA
• NCBI Official Synonym Full Names: endoplasmic reticulum protein 29
• NCBI Official Symbol: ERP29
• NCBI Official Synonym Symbols: ERp28; ERp31; PDIA9; PDI-DB; C12orf8; HEL-S-107
• NCBI Protein Information: endoplasmic reticulum resident protein 29; endoplasmic reticulum lumenal protein ERp28; endoplasmic reticulum resident protein 28; endoplasmic reticulum resident protein 31; epididymis secretory protein Li 107; protein disulfide isomerase family A, member 9
• UniProt Protein Name: Endoplasmic reticulum resident protein 29
• UniProt Gene Name: ERP29
• UniProt Entry Name: ERP29_HUMAN

NCBI Description

This gene encodes a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum (ER). The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

ERP29: Does not seem to be a disulfide isomerase. Plays an important role in the processing of secretory proteins within the endoplasmic reticulum (ER), possibly by participating in the folding of proteins in the ER.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 12q24.13

Cellular Component: transport vesicle; smooth endoplasmic reticulum; cell surface; membrane; endoplasmic reticulum lumen; endoplasmic reticulum; melanosome

Molecular Function: protein binding; protein homodimerization activity; chaperone binding; protein disulfide isomerase activity

Biological Process: intracellular protein transport; negative regulation of protein secretion; protein folding; activation of MAPK activity; protein unfolding; protein secretion; positive regulation of protein amino acid phosphorylation