Western Blot (WB)
(Western Blot detection against Immunogen (37.84kD).)
Mouse anti-Human Dihydropyrimidine Dehydrogenase Monoclonal Antibody | anti-DPD antibody
Dihydropyrimidine Dehydrogenase (DPD, DPYD, DHP, DHPDHase, Dihydrothymine Dehydrogenase, Dihydrouracil Dehydrogenase, MGC70799, MGC132008) (AP)
Western Blot (WB)
(Western Blot detection against Immunogen (37.84kD).)
Western Blot (WB)
(Western Blot detection against Immunogen (37.84kD).)
Western Blot (WB)
(DPYD monoclonal antibody, Western Blot analysis of DPYD expression in HeLa.)
Western Blot (WB)
(DPYD monoclonal antibody, Western Blot analysis of DPYD expression in HeLa.)
Western Blot (WB)
(DPYD monoclonal antibody. Western Blot analysis of DPYD expression in Hela NE.)
Western Blot (WB)
(DPYD monoclonal antibody. Western Blot analysis of DPYD expression in Hela NE.)
Immunofluorescence (IF)
(Immunofluorescence of monoclonal antibody to DPYD on HeLa cell. [antibody concentration 10ug/ml].)
Immunofluorescence (IF)
(Immunofluorescence of monoclonal antibody to DPYD on HeLa cell. [antibody concentration 10ug/ml].)
Testing Data
(Detection limit for recombinant GST tagged DPYD is ~0.1ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged DPYD is ~0.1ng/ml as a capture antibody.)
NCBI and Uniprot Product Information
Uniprot Description
DPYD: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil. Homodimer. Found in most tissues with greatest activity found in liver and peripheral blood mononuclear cells. Belongs to the dihydropyrimidine dehydrogenase family.
Protein type: Other Amino Acids Metabolism - beta-alanine; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - other enzymes; Nucleotide Metabolism - pyrimidine; EC 1.3.1.2; Cofactor and Vitamin Metabolism - pantothenate and CoA biosynthesis
Chromosomal Location of Human Ortholog: 1p22
Cellular Component: cytoplasm; cytosol
Molecular Function: protein homodimerization activity; FAD binding; metal ion binding; dihydroorotate dehydrogenase activity; 4 iron, 4 sulfur cluster binding; dihydropyrimidine dehydrogenase (NADP+) activity; NADP binding
Biological Process: pyrimidine nucleoside catabolic process; pyrimidine base metabolic process; nucleobase, nucleoside and nucleotide metabolic process; UMP biosynthetic process; uracil catabolic process; thymine catabolic process; beta-alanine biosynthetic process; purine base catabolic process; pyrimidine base catabolic process; thymidine catabolic process
Disease: Dihydropyrimidine Dehydrogenase Deficiency
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Product Notes
The DPD dpyd (Catalog #AAA6130936) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Dihydropyrimidine Dehydrogenase (DPD, DPYD, DHP, DHPDHase, Dihydrothymine Dehydrogenase, Dihydrouracil Dehydrogenase, MGC70799, MGC132008) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Dihydropyrimidine Dehydrogenase can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the DPD dpyd for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Dihydropyrimidine Dehydrogenase, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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