Flow Cytometry (FC/FACS)
(Flow cytometric analysis of Human TNFRSF10C(CD263) expression on human whole blood granulocytes. Cells were stained with purified anti-Human TNFRSF10C(CD263), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes.)
Rabbit anti-Human DcR1/TRAILR3 Monoclonal Antibody | anti-TNFRSF10C antibody
Recombinant Anti-DcR1/TRAILR3 Antibody, Rabbit Monoclonal
Gene Names
TNFRSF10C; LIT; DCR1; TRID; CD263; TRAILR3; TRAIL-R3; DCR1-TNFR
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Purity
Protein A
Synonyms
DcR1/TRAILR3; Monoclonal Antibody; Recombinant Anti-DcR1/TRAILR3 Antibody; Rabbit Monoclonal; TRAILR3/TNFRSF10C Antibody; Rabbit MAb; tumor necrosis factor receptor superfamily member 10c; Anti-CD263 Antibody; Anti-DCR1 Antibody; Anti-DCR1-TNFR Antibody; Anti-LIT Antibody; Anti-TRAIL-R3 Antibody; Anti-TRAILR3 Antibody; Anti-TRID Antibody; anti-TNFRSF10C antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
003
Specificity
Human TRAILR3/TNFRSF10C
Purity/Purification
Protein A
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-TNFRSF10C antibody
Flow Cytometry (FC/FACS/FCM)
Application Notes
FC/FACS/FCM: 1:25-1:100
Antibody Type
Recombinant Antibody
Immunogen
Recombinant Human TRAILR3/TNFRSF10C Protein
Conjugation
Unconjugated
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human TRAILR3/TNFRSF10C (rh TRAILR3/TNFRSF10C).
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of Human TNFRSF10C(CD263) expression on human whole blood granulocytes. Cells were stained with purified anti-Human TNFRSF10C(CD263), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes.)
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of Human TNFRSF10C(CD263) expression on human whole blood granulocytes. Cells were stained with purified anti-Human TNFRSF10C(CD263), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes.)
Related Product Information for anti-TNFRSF10C antibody
TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most PC cell lines (except CFPAC-1). Inactivation of TNFRSF10C by CpG island (CGI) hypermethylation can play an important role in PC progression and be potentially useful as a marker and a new therapeutic approach for PC.
Product Categories/Family for anti-TNFRSF10C antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27,407 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 10C
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily member 10c
NCBI Official Symbol
TNFRSF10C
NCBI Official Synonym Symbols
LIT; DCR1; TRID; CD263; TRAILR3; TRAIL-R3; DCR1-TNFR
NCBI Protein Information
tumor necrosis factor receptor superfamily member 10C
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 10C
Protein Family
UniProt Gene Name
TNFRSF10C
UniProt Synonym Gene Names
DCR1; LIT; TRAILR3; TRID; DcR1; TRAIL receptor 3; TRAIL-R3
UniProt Entry Name
TR10C_HUMAN
Uniprot Description
TRAIL-R3: Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand. Higher expression in normal tissues than in tumor cell lines. Highly expressed in peripheral blood lymphocytes, spleen, skeletal muscle, placenta, lung and heart.
Protein type: Membrane protein, GPI anchor
Chromosomal Location of Human Ortholog: 8p22-p21
Cellular Component: integral to plasma membrane
Molecular Function: transmembrane receptor activity; TRAIL binding
Biological Process: apoptosis; signal transduction
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Product Notes
The TNFRSF10C tnfrsf10c (Catalog #AAA8102727) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Anti-DcR1/TRAILR3 Antibody, Rabbit Monoclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DcR1/TRAILR3 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS/FCM). FC/FACS/FCM: 1:25-1:100. Researchers should empirically determine the suitability of the TNFRSF10C tnfrsf10c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DcR1/TRAILR3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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