Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human brain tissue slide using MBS768321 (CX3CL1 Antibody) at dilution of 1:200)
Mouse CX3CL1 Monoclonal Antibody | anti-CX3CL1 antibody
CX3CL1 Mouse Monoclonal
Gene Names
CX3CL1; NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin
Reactivity
Human; other species are not tested.
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
> 95% as determined by SDS-PAGE/Protein A+G purification
Synonyms
CX3CL1; Monoclonal Antibody; CX3CL1 Mouse Monoclonal; FKN; NTT; SCYD1; anti-CX3CL1 antibody
Host
Mouse
Reactivity
Human; other species are not tested.
Clonality
Monoclonal
Isotype
IgG1
Clone Number
5D1
Specificity
Please decide the specificity by homology.
Purity/Purification
> 95% as determined by SDS-PAGE/Protein A+G purification
Form/Format
Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3
Applicable Applications for anti-CX3CL1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: WB: 1:500-1:2000; IHC: 1:50-1:500
Immunogen
Chemokine (C-X3-C motif) ligand 1
Preparation and Storage
Store at -20°C for 24 months. (Avoid repeated freeze / thaw cycles.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human brain tissue slide using MBS768321 (CX3CL1 Antibody) at dilution of 1:200)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human brain tissue slide using MBS768321 (CX3CL1 Antibody) at dilution of 1:200)
Western Blot (WB)
(PC-3 cells were subjected to SDS PAGE followed by western blot with MBS768321 (CX3CL1 antibody) at dilution of 1:1000)
Western Blot (WB)
(PC-3 cells were subjected to SDS PAGE followed by western blot with MBS768321 (CX3CL1 antibody) at dilution of 1:1000)
Related Product Information for anti-CX3CL1 antibody
Acts as a ligand for both CX3CL1 and integrins. Binds to CX3CR1(PubMed:23125415, PubMed:9931005, PubMed:21829356). Binds to integrins ITGAV:ITGB3 and ITGA4:ITGB1. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site(site 1) in integrins. In the absence of CX3CR1, binds to a second site(site 2) in integrins which is distinct from site 1 and enhances the binding of other integrin ligands to site 1(PubMed:23125415, PubMed:24789099). The soluble form is chemotactic for T-cells and monocytes and not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium(PubMed:9024663, PubMed:9177350).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
90 kDa
NCBI Official Full Name
CX3CL1
NCBI Official Synonym Full Names
C-X3-C motif chemokine ligand 1
NCBI Official Symbol
CX3CL1
NCBI Official Synonym Symbols
NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin
NCBI Protein Information
fractalkine
UniProt Protein Name
CX3CL1 protein
Protein Family
UniProt Gene Name
CX3CL1
UniProt Entry Name
Q6I9S9_HUMAN
Research Articles on CX3CL1
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Product Notes
The CX3CL1 cx3cl1 (Catalog #AAA768321) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CX3CL1 Mouse Monoclonal reacts with Human; other species are not tested. and may cross-react with other species as described in the data sheet. AAA Biotech's CX3CL1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Recommended dilution: WB: 1:500-1:2000; IHC: 1:50-1:500. Researchers should empirically determine the suitability of the CX3CL1 cx3cl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CX3CL1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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