Mouse CRX Monoclonal Antibody | anti-CRX antibody

CRX (Cone-rod Homeobox, CORD2, CRD, LCA7, OTX3) (FITC)

Cat. Num. AAA6177710

• Gene Names: CRX; CRD; LCA7; OTX3; CORD2
• Applications: ELISA, Immunofluorescence, Western Blot
• Purity: Purified
• Synonyms: CRX; Monoclonal Antibody; CRX (Cone-rod Homeobox; CORD2; CRD; LCA7; OTX3) (FITC); Cone-rod Homeobox; OTX3; anti-CRX antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2b,k
• Clone Number: 4A12
• Specificity: Recognizes CRX.
• Purity/Purification: Purified
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
• Sequence Length: 299

• Applicable Applications for anti-CRX antibody: ELISA (EIA), Immunofluorescence (IF), Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: CRX (AAH16664, 1aa-299aa) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD.
• Immunogen Sequence: MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLSPMVPQLGGPALSPLSGPSVGPSLAQSPTSLSGQSYGAYSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL
• Conjugate: FITC
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer.; ; FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of CRX expression in transfected 293T cell line by CRX monoclonal antibody (M06), clone 4A12.Lane 1: CRX transfected lysate (32.3 KDa).Lane 2: Non-transfected lysate.)

Immunofluorescence (IF)

(Immunofluorescence of monoclonal antibody to CRX on HeLa cell. [antibody concentration 10 ug/ml])

Immunofluorescence (IF)

(Immunofluorescence of monoclonal antibody to CRX on HeLa cell. [antibody concentration 10 ug/ml])

Related Product Information for anti-CRX antibody

The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq]

Product Categories/Family for anti-CRX antibody

Antibodies; Transcription Factors; Homeobox (HOX)

NCBI and Uniprot Product Information

• NCBI GI #: 16741738
• NCBI GeneID: 1406
• NCBI Official Full Name: CRX protein
• NCBI Official Synonym Full Names: cone-rod homeobox
• NCBI Official Symbol: CRX
• NCBI Official Synonym Symbols: CRD; LCA7; OTX3; CORD2
• NCBI Protein Information: cone-rod homeobox protein
• Protein Family: Cone-rod homeobox protein

NCBI Description

The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]