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Immunohistochemistry (IHC) (Anti-CPNE6 / N-COPINE antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Mouse anti-Human CPNE6 / N-COPINE Monoclonal Antibody | anti-CPNE6 antibody

Mouse Monoclonal [clone 6.4_1B4] (IgG2a) to Human CPNE6 / N-COPINE

Reactivity
Human
Applications
Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
Purity
Protein A/G Purified
Synonyms
CPNE6 / N-COPINE; Monoclonal Antibody; Mouse Monoclonal [clone 6.4_1B4] (IgG2a) to Human CPNE6 / N-COPINE; Anti-CPNE6 / N-COPINE Antibody (clone 6.4_1B4) IHC-plus; CPNE6; Copine VI; Copine VI (neuronal); Copine-6; Neuronal-copine; N-COPINE; Neuronal copine; Human CPNE6; anti-CPNE6 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
6.4_1B4
Specificity
Human CPNE6 / N-COPINE
Purity/Purification
Protein A/G Purified
Form/Format
PBS, 0.02% sodium azide
Sequence Length
557
Applicable Applications for anti-CPNE6 antibody
Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB), Immunoprecipitation (IP)
Application Notes
ICC (10 ug/ml), IHC-P (10 ug/ml), IP, WB (1 ug/ml)
Target Species
Human
Immunogen Description
HeLa cells
Immunogen Type
Cells
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.

Immunohistochemistry (IHC)

(Anti-CPNE6 / N-COPINE antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-CPNE6 / N-COPINE antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
67,641 Da
NCBI Official Full Name
copine-6 isoform 2
NCBI Official Synonym Full Names
copine VI (neuronal)
NCBI Official Symbol
CPNE6
NCBI Protein Information
copine-6; N-copine
UniProt Protein Name
Copine-6
Protein Family
UniProt Gene Name
CPNE6
UniProt Synonym Gene Names
N-copine
UniProt Entry Name
CPNE6_HUMAN

NCBI Description

This gene encodes a member of the copine family. Members of this family are calcium-dependent, phospholipid-binding proteins with C2 domains, two calcium- and phospholipid-binding domains. Through their domain structure and lipid binding capabilities, these proteins may play a role in membrane trafficking. This protein is thought to be brain-specific and has a domain structure of two N-terminal C2 domains and one von Willebrand factor A domain. It may have a role in synaptic plasticity. [provided by RefSeq, Jul 2013]

Uniprot Description

CPNE6: May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties. May have a role in synaptic plasticity. Belongs to the copine family.

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: membrane; axon; dendrite

Molecular Function: transporter activity; phosphatidylserine binding; calcium ion binding

Biological Process: vesicle-mediated transport; synaptic transmission; nervous system development; lipid metabolic process

Research Articles on CPNE6

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Product Notes

The CPNE6 cpne6 (Catalog #AAA249118) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone 6.4_1B4] (IgG2a) to Human CPNE6 / N-COPINE reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CPNE6 / N-COPINE can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB), Immunoprecipitation (IP). ICC (10 ug/ml), IHC-P (10 ug/ml), IP, WB (1 ug/ml). Researchers should empirically determine the suitability of the CPNE6 cpne6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CPNE6 / N-COPINE, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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