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Testing Data (Staining of Cx45 transfected rat C6 cells.)

Mouse anti-Human, Rat Connexin 45 Monoclonal Antibody | anti-CX45 antibody

Connexin 45 (GJC1, Gap Junction protein, gamma 1, 45kD, Cx45, CX45, DKFZp686P0738, Gap junction alpha-7 protein, Gap junction gamma-1 protein, GJA7) (MaxLight 550)

Gene Names
GJC1; CX45; GJA7
Reactivity
Human, Rat
Applications
Immunocytochemistry, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
Connexin 45; Monoclonal Antibody; Connexin 45 (GJC1; Gap Junction protein; gamma 1; 45kD; Cx45; CX45; DKFZp686P0738; Gap junction alpha-7 protein; Gap junction gamma-1 protein; GJA7) (MaxLight 550); anti-CX45 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2Q265
Specificity
Recognizes human Connexin 45. Due to sequence homologies, this antibody is also expected to react with canine (100% homology) and mouse (92% homology) Connexin 45. Also confirmed to work on rat C6 cells.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.
Applicable Applications for anti-CX45 antibody
Immunocytochemistry (ICC), Western Blot (WB)
Immunogen
Synthetic peptide corresponding to aa354-367 of human connexin 45; [H-Gln-Ala-Tyr-Ser-His-Gln-Asn-Asn-Pro-His-Gly-Pro-Arg-Glu-Cys- OH], conjugated to KLH.
Conjugate
MaxLight550
Preparation and Storage
Store at 4 degree C. Do Not Freeze.

Testing Data

(Staining of Cx45 transfected rat C6 cells.)

Testing Data (Staining of Cx45 transfected rat C6 cells.)
Product Categories/Family for anti-CX45 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
45,470 Da
NCBI Official Full Name
gap junction gamma-1 protein
NCBI Official Synonym Full Names
gap junction protein, gamma 1, 45kDa
NCBI Official Symbol
GJC1
NCBI Official Synonym Symbols
CX45; GJA7
NCBI Protein Information
gap junction gamma-1 protein; connexin 45; connexin-45; gap junction alpha-7 protein
UniProt Protein Name
Gap junction gamma-1 protein
UniProt Gene Name
GJC1
UniProt Synonym Gene Names
GJA7; Cx45
UniProt Entry Name
CXG1_HUMAN

NCBI Description

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008]

Uniprot Description

GJC1: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Gamma-type subfamily.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Cell adhesion

Chromosomal Location of Human Ortholog: 17q21.31

Cellular Component: connexon complex; endoplasmic reticulum membrane; plasma membrane; gap junction; integral to membrane

Molecular Function: ion channel activity; gap junction channel activity

Biological Process: cardiac muscle development; synaptic transmission; intercellular junction assembly; visual perception; muscle contraction; gap junction assembly; transport; vasculogenesis; cell development

Research Articles on CX45

Similar Products

Product Notes

The CX45 gjc1 (Catalog #AAA6245903) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Connexin 45 (GJC1, Gap Junction protein, gamma 1, 45kD, Cx45, CX45, DKFZp686P0738, Gap junction alpha-7 protein, Gap junction gamma-1 protein, GJA7) (MaxLight 550) reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Connexin 45 can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Western Blot (WB). Researchers should empirically determine the suitability of the CX45 gjc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Connexin 45, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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