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Immunohistochemistry (IHC) (Anti-C9 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.)

Mouse anti-Human Complement C9 Monoclonal Antibody | anti-C9 antibody

Mouse Monoclonal [clone 64E9] (IgG1,k) to Human Complement C9

Gene Names
C9; C9D; ARMD15
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Ammonium sulfate precipitation
Synonyms
Complement C9; Monoclonal Antibody; Mouse Monoclonal [clone 64E9] (IgG1; k) to Human Complement C9; Anti-Complement C9 Antibody (clone 64E9) IHC-plus; C9; Complement component 9; Complement component C9; Human Complement C9; anti-C9 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
64E9
Purity/Purification
Ammonium sulfate precipitation
Form/Format
HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol
Concentration
2 mg/ml (varies by lot)
Sequence Length
559
Applicable Applications for anti-C9 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes
IHC-P (1:200), WB (1:2000)
Target Species
Human
Immunogen Description
Protein purified from Human plasma.
Immunogen
Complement C9 antibody was raised against protein purified from Human plasma.
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C; Avoid freeze-thaw cycles.

Immunohistochemistry (IHC)

(Anti-C9 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.)

Immunohistochemistry (IHC) (Anti-C9 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.)

Western Blot (WB)

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Western Blot (WB) ( )
Product Categories/Family for anti-C9 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
735
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
63,173 Da
NCBI Official Full Name
complement component C9
NCBI Official Synonym Full Names
complement component 9
NCBI Official Symbol
C9
NCBI Official Synonym Symbols
C9D; ARMD15
NCBI Protein Information
complement component C9
UniProt Protein Name
Complement component C9
Protein Family
UniProt Gene Name
C9
UniProt Entry Name
CO9_HUMAN

NCBI Description

This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. [provided by RefSeq, Feb 2009]

Uniprot Description

C9: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC. Defects in C9 are a cause of complement component 9 deficiency (C9D). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Belongs to the complement C6/C7/C8/C9 family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Apoptosis; Extracellular matrix

Chromosomal Location of Human Ortholog: 5p14-p12

Cellular Component: membrane attack complex; integral to plasma membrane; cytoplasm; extracellular region; plasma membrane

Biological Process: complement activation, alternative pathway; regulation of complement activation; innate immune response; hemolysis by symbiont of host red blood cells; complement activation, classical pathway

Disease: Macular Degeneration, Age-related, 15; Complement Component 9 Deficiency

Research Articles on C9

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Product Notes

The C9 c9 (Catalog #AAA245734) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone 64E9] (IgG1,k) to Human Complement C9 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Complement C9 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB). IHC-P (1:200), WB (1:2000). Researchers should empirically determine the suitability of the C9 c9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Complement C9, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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