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Western Blot (WB)
(Western Blot detection against Immunogen ((64.24kD).)
Mouse anti-Human CLCN2 Monoclonal Antibody | anti-CLCN2 antibody
CLCN2 (Chloride Channel Protein 2, ClC-2) (FITC)
Gene Names
CLCN2; CLC2; ECA2; ECA3; EGI3; EGMA; EJM6; EJM8; CIC-2; EGI11; LKPAT; clC-2
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
CLCN2; Monoclonal Antibody; CLCN2 (Chloride Channel Protein 2; ClC-2) (FITC); anti-CLCN2 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
3E1
Specificity
Recognizes human CLCN2.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Applicable Applications for anti-CLCN2 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length recombinant corresponding to aa38-387 from human CLCN2 (AAH21578.1) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
TVSTAVIVFELTGQIAHILPVMIVVILANAVAQSLQPSLYDSIIRIKKLPYLPELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILLGSIERSQVVALLGAQLSPARRRQHMQERRATQTSPLSDQEGPPTPEASVCFQVNTEDSAFPAARGETHKPLKPALKRGPSVTRNLGESPTGSAESAGIALRSLFCGSPPPEAASEKLESCEKRKLKRVRISLASDADLEGEMSPEETHTIFSLLGVDHAYVTSIGRLIGIVTLKELRKAIEGSVTAQGVKVRPPLASFRDSATSSSDTETTEVHALWGPHSRHGLPREGSPSDSDDKCQ
Conjugate
FITC
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot detection against Immunogen ((64.24kD).)
Western Blot (WB)
(Western Blot detection against Immunogen ((64.24kD).)
Western Blot (WB)
(CLCN2 monoclonal antibody, Western Blot analysis of CLCN2 expression in Hela NE.)
Western Blot (WB)
(CLCN2 monoclonal antibody, Western Blot analysis of CLCN2 expression in Hela NE.)
Western Blot (WB)
(Western Blot analysis of CLCN2 expression in transfected 293T cell line by CLCN2 monoclonal antibody. Lane 1: CLCN2 transfected lysate (96.8kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of CLCN2 expression in transfected 293T cell line by CLCN2 monoclonal antibody. Lane 1: CLCN2 transfected lysate (96.8kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western blot analysis of CLCN2 over-expressed 293 cell line, cotransfected with CLCN2 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with CLCN2 monoclonal antibody. GAPDH (36.1kD) used as specificity and loading control.)
Western Blot (WB)
(Western blot analysis of CLCN2 over-expressed 293 cell line, cotransfected with CLCN2 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with CLCN2 monoclonal antibody. GAPDH (36.1kD) used as specificity and loading control.)
Related Product Information for anti-CLCN2 antibody
Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport.
Product Categories/Family for anti-CLCN2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
95,399 Da
NCBI Official Full Name
Homo sapiens chloride channel 2, mRNA
NCBI Official Synonym Full Names
chloride voltage-gated channel 2
NCBI Official Symbol
CLCN2
NCBI Official Synonym Symbols
CLC2; ECA2; ECA3; EGI3; EGMA; EJM6; EJM8; CIC-2; EGI11; LKPAT; clC-2
NCBI Protein Information
chloride channel protein 2
Protein Family
NCBI Description
This gene encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
Research Articles on CLCN2
Similar Products
Product Notes
The CLCN2 (Catalog #AAA6146531) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CLCN2 (Chloride Channel Protein 2, ClC-2) (FITC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CLCN2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the CLCN2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLCN2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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