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Immunohistochemistry (IHC) (Immunohistochemistry staining of MO47022 on human colon tissue.)

Mouse anti-Human CK19 (Cytokeratin 19) Monoclonal Antibody | anti-CK19 antibody

CK19 (Cytokeratin 19)

Gene Names
KRT19; K19; CK19; K1CS
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
CK19 (Cytokeratin 19); Monoclonal Antibody; anti-CK19 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse IgG
Form/Format
Affinity Purified antibody
Liquid with PBS buffer, pH7.4 with 0.02% Sodium Azide
Applicable Applications for anti-CK19 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:1,000-3,000
Immunogen
Recombinant Human Cytokeratin 19
Preparation and Storage
The product can be stored undiluted for several weeks at 4 degree C. Dilute only immediately before use. Aliquot and store at -20 degree C for long term. Avoid freeze thaw-cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry staining of MO47022 on human colon tissue.)

Immunohistochemistry (IHC) (Immunohistochemistry staining of MO47022 on human colon tissue.)
Related Product Information for anti-CK19 antibody
Cytokeratin 19 Antibody is a intermediate filament protein making up the structural integrity of epithelial cells specifically found in the periderm. Cytokeratin 19 (CK19) have been used in studies for detection of tumor cells in bone marrow, lymph nodes, and even in peripheral blood.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44,106 Da
NCBI Official Full Name
keratin, type I cytoskeletal 19
NCBI Official Synonym Full Names
keratin 19
NCBI Official Symbol
KRT19
NCBI Official Synonym Symbols
K19; CK19; K1CS
NCBI Protein Information
keratin, type I cytoskeletal 19; CK-19; keratin-19; cytokeratin 19; cytokeratin-19; keratin, type I, 40-kd; 40-kDa keratin intermediate filament
UniProt Protein Name
Keratin, type I cytoskeletal 19
UniProt Gene Name
KRT19
UniProt Synonym Gene Names
CK-19; K19
UniProt Entry Name
K1C19_HUMAN

NCBI Description

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]

Uniprot Description

K19: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 19 differs from all other IF proteins in lacking the C-terminal tail domain. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 17q21.2

Cellular Component: dystrophin-associated glycoprotein complex; costamere; intermediate filament; Z disc; sarcolemma

Molecular Function: protein binding; structural constituent of cytoskeleton; structural constituent of muscle; protein complex binding

Biological Process: viral reproduction; response to estrogen stimulus; sarcomere organization

Research Articles on CK19

Similar Products

Product Notes

The CK19 krt19 (Catalog #AAA556121) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CK19 (Cytokeratin 19) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CK19 (Cytokeratin 19) can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:1,000-3,000. Researchers should empirically determine the suitability of the CK19 krt19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CK19 (Cytokeratin 19), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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