Mouse Chymotrypsin Monoclonal Antibody | anti-CTRC antibody

Chymotrypsin Monoclonal Antibody

Gene Names

CTRC; CLCR; ELA4; CTRC

Applications

Western Blot

Synonyms

Chymotrypsin; Monoclonal Antibody; Chymotrypsin Monoclonal Antibody; Anti-Chymotrypsin; anti-CTRC antibody

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Cat. Num. AAA190110 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Host

Mouse

Clonality

Monoclonal

Isotype

IgG3

Specificity

Anti-Chymotrypsin [Human pancreatic chymotrypsin (4 clones). LP]
These antibodies do not cross-react with human pancreatic trypsin.

Form/Format

1 ml ascites or 1 mg Protein G-purified antibody in PBS, pH 7.4

Sequence Length

Applicable Applications for anti-CTRC antibody

Western Blot, Immunoassay

Application Notes

These antibodies may be used in immunoassays and Western Blotting to identify chymotrypsin. Other applications are under investigation

Antigen

Purified human pancreatic chymotrypsin.

Activity

Ig mg/ml* :9.2
ELISA Titer**:1:204,800
(Note: * Determined by radial immunodiffusion for several lots of ascites.
**ELISA is an indirect assay against human pancreatic chymotrypsin on the solid phase. Titers represent endpoint dilutions that achieve absorbance values >= 0.1)

Stabilizer

None

Preservatives

None. Available on request

Dilutions Instructions

Dilute in PBS or medium which is identical to that used in the assay system.

Preparation and Storage

These antibodies are stable for at least one (1) year at -20 degree C to -70 degree C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.

Product Categories/Family for anti-CTRC antibody

Enzyme and Enzyme Inhibitor Antibodies

NCBI and Uniprot Product Information

NCBI GI #

2196868

NCBI GeneID

11330

UniProt Accession #

Q99895; Q68DR9

Molecular Weight

7,728 Da

NCBI Official Full Name

chymotrypsin

NCBI Official Synonym Full Names

chymotrypsin C (caldecrin)

NCBI Official Symbol

CTRC

NCBI Official Synonym Symbols

CLCR; ELA4; CTRC

NCBI Protein Information

chymotrypsin C; caldecrin; elastase 4; elastase IV; serum calcium decreasing factor

UniProt Protein Name

Putative uncharacterized protein DKFZp779K0837

Protein Family

Chymotrypsin

UniProt Gene Name

DKFZp779K0837

UniProt Synonym Gene Names

CTRC

UniProt Entry Name

Q68DR9_HUMAN

NCBI Description

This gene encodes a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq]

Uniprot Description

CTRC: Has chymotrypsin-type protease activity and hypocalcemic activity. Genetic variations in CTRC can predispose to chronic pancreatitis by diminishing its protective trypsin-degrading activity. Belongs to the peptidase S1 family. Elastase subfamily.

Protein type: EC 3.4.21.2; Protease

Chromosomal Location of Human Ortholog: 1p36.21

Molecular Function: peptidase activity; serine-type endopeptidase activity

Biological Process: proteolysis

Disease: Pancreatitis, Hereditary

Research Articles on CTRC

1. Novel CTRC gene variations and single nucleotide polymorphisms are associated with chymotrypsin C in a Chinese population.
2. Observational study of gene-disease association. (HuGE Navigator)
3. Study analyzed the gene encoding the trypsin-degrading enzyme chymotrypsin C in German subjects with idiopathic or hereditary chronic pancreatitis; 2 alterations in this gene were significantly overrepresented in the pancreatitis group.

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Product Notes

The CTRC dkfzp779k0837 (Catalog #AAA190110) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Chymotrypsin can be used in a range of immunoassay formats including, but not limited to, Western Blot, Immunoassay. These antibodies may be used in immunoassays and Western Blotting to identify chymotrypsin. Other applications are under investigation. Researchers should empirically determine the suitability of the CTRC dkfzp779k0837 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Chymotrypsin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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