Mouse anti-Human Chorionic Gonadotropin c2 Monoclonal Antibody | anti-PLA2G4A antibody
Chorionic Gonadotropin c2 (hCGc2)
Purified by ammonium sulfate precipitation.
Purified by ammonium sulfate precipitation.
NCBI and Uniprot Product Information
Uniprot Description
Function: Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response
By similarity.
Catalytic activity: Phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate.2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.
Enzyme regulation: Stimulated by agonists such as ATP, EGF, thrombin and bradykinin as well as by cytosolic Ca2+
By similarity.
Subunit structure: Interacts with KAT5
By similarity.
Subcellular location: Cytoplasm
By similarity. Cytoplasmic vesicle
By similarity. Note: Translocates to membrane vesicles in a calcium-dependent fashion
By similarity.
Tissue specificity: Detected in granulosa cells after stimulation with chorionic gonadotropin (at protein level). Ref.1
Developmental stage: Highly expressed in granulosa cells of ovulatory follicles. Detected at low levels in granulosa cells during the rest of the estrous cycle.
Domain: The N-terminal C2 domain associates with lipid membranes upon calcium binding. It modulates enzyme activity by presenting the active site to its substrate in response to elevations of cytosolic Ca2+
By similarity.
Post-translational modification: Activated by phosphorylation at both Ser-505 and Ser-727
By similarity.
Sequence similarities: Contains 1 C2 domain.Contains 1 PLA2c domain.
Research Articles on PLA2G4A
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Product Notes
The PLA2G4A pla2g4a (Catalog #AAA603540) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Chorionic Gonadotropin c2 (hCGc2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Chorionic Gonadotropin c2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). ELISA, Optimal working dilutions to be determined by researcher. Researchers should empirically determine the suitability of the PLA2G4A pla2g4a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Chorionic Gonadotropin c2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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