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Immunohistochemistry (IHC) (Formalin-fixed, paraffin-embedded placenta stained with hCG beta MAb (SPM529). Note specific membrane staining.)

Mouse anti-Human Chorionic Gonadotropin, beta Monoclonal Antibody | anti-hCGb antibody

Chorionic Gonadotropin, Human, beta (hCGb) (Biotin)

Gene Names
CGB; CGB3; CGB5; CGB7; CGB8; hCGB
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Purified by Protein A/G Affinity Chromatography.
Synonyms
Chorionic Gonadotropin; beta; Monoclonal Antibody; Human; beta (hCGb) (Biotin); CG-beta; CGB3; CGB5; CGB7; CGB8; Choriogonadotropin Subunit beta; hCGB; anti-hCGb antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
SPM529
Specificity
Recognizes human HCG-beta.
Purity/Purification
Purified by Protein A/G Affinity Chromatography.
Form/Format
Supplied as a liquid in 10mM PBS. No preservative added. BSA-Free. Labeled with Biotin.
Applicable Applications for anti-hCGb antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
WB: 0.5-1ug/ml
IHC: 0.5-1ug/ml; 30 min RT
Applications are based on unconjugated antibody.
Immunogen
Recombinant hCG beta protein. Cellular Localization: Cytoplasmic, secreted
Conjugate
Biotin
Positive Control
Placenta
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(Formalin-fixed, paraffin-embedded placenta stained with hCG beta MAb (SPM529). Note specific membrane staining.)

Immunohistochemistry (IHC) (Formalin-fixed, paraffin-embedded placenta stained with hCG beta MAb (SPM529). Note specific membrane staining.)
Product Categories/Family for anti-hCGb antibody
References
1. Cocquebert M et. al. Am J Physiol Endocrinol Metab. 2012;303(8):E950-8.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
17,739 Da
NCBI Official Full Name
choriogonadotropin subunit beta
NCBI Official Synonym Full Names
chorionic gonadotropin, beta polypeptide
NCBI Official Symbol
CGB
NCBI Official Synonym Symbols
CGB3; CGB5; CGB7; CGB8; hCGB
NCBI Protein Information
choriogonadotropin subunit beta; CG-beta; chorionic gonadotropin beta chain; chorionic gonadotrophin chain beta; chorionic gonadotropin beta subunit; chorionic gonadotropin beta 3 subunit
UniProt Protein Name
Choriogonadotropin subunit beta
UniProt Gene Name
CGB
UniProt Synonym Gene Names
CGB3; CG-beta
UniProt Entry Name
CGHB_HUMAN

NCBI Description

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]

Uniprot Description

CGB: Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. Belongs to the glycoprotein hormones subunit beta family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Inhibitor; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: extracellular region

Molecular Function: hormone activity

Biological Process: cellular protein metabolic process; cell-cell signaling; apoptosis; peptide hormone processing; female gamete generation; signal transduction

Research Articles on hCGb

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Product Notes

The hCGb cgb (Catalog #AAA6124254) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Chorionic Gonadotropin, Human, beta (hCGb) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Chorionic Gonadotropin, beta can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). WB: 0.5-1ug/ml IHC: 0.5-1ug/ml; 30 min RT Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the hCGb cgb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Chorionic Gonadotropin, beta, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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