Mouse Cholera Toxin, alpha, Vibrio cholerae Monoclonal Antibody
Cholera Toxin, alpha, Vibrio cholerae
Applications
ELISA
Purity
PurifiedPurified by ammonium sulfate precipitation.
Synonyms
Cholera Toxin; alpha; Vibrio cholerae; Monoclonal Antibody; Anti -Cholera Toxin; anti-Cholera Toxin; Vibrio cholerae antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgM
Clone Number
3j3
Specificity
Recognizes the alpha chain of the V. cholerae toxin.
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Purified by ammonium sulfate precipitation.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
Applicable Applications for anti-Cholera Toxin, alpha, Vibrio cholerae antibody
ELISA (EL/EIA)
Application Notes
Suitable for use in ELISA.
Immunogen
Vibrio cholerae extract
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-Cholera Toxin, alpha, Vibrio cholerae antibody
The cholera holotoxin consists of a pentameric ring of Beta subunits whose central pore is occupied by the Alpha subunit. The Alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The Alpha subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.
Product Categories/Family for anti-Cholera Toxin, alpha, Vibrio cholerae antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
cholera toxin
Uniprot Description
The A1 chain catalyzes the ADP-ribosylation of Gs alpha, a GTP-binding regulatory protein, to activate the adenylate cyclase. This leads to an overproduction of cAMP and eventually to a hypersecretion of chloride and bicarbonate followed by water, resulting in the characteristic cholera stool. The A2 chain tethers A1 to the pentameric ring.
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Product Notes
The Cholera Toxin, alpha, Vibrio cholerae (Catalog #AAA600903) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Cholera Toxin, alpha, Vibrio cholerae can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). Suitable for use in ELISA. Researchers should empirically determine the suitability of the Cholera Toxin, alpha, Vibrio cholerae for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cholera Toxin, alpha, Vibrio cholerae, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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