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Quality Control (Left: Western blot analysis of immunized recombinant protein, using anti-CHES1 monoclonal antibody.)

Mouse anti-Human CHES1 Monoclonal Antibody | anti-CHES1 antibody

Mouse monoclonal antibody Anti-Human CHES1

Gene Names
FOXN3; CHES1; PRO1635; C14orf116
Reactivity
Human
Applications
Dot Blot
Synonyms
CHES1; Monoclonal Antibody; Mouse monoclonal antibody Anti-Human CHES1; checkpoint suppressor 1 (CHES1); FOXN3; PRO1635; C14orf116; anti-CHES1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
CHESC9H4
Concentration
100 ug/ml (1.0 ml) (varies by lot)
Sequence Length
7907
Applicable Applications for anti-CHES1 antibody
Dot Blot (DB)
Preparation
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility
Filtered through a 0.22 um membrane.

Quality Control

(Left: Western blot analysis of immunized recombinant protein, using anti-CHES1 monoclonal antibody.)

Quality Control (Left: Western blot analysis of immunized recombinant protein, using anti-CHES1 monoclonal antibody.)
Related Product Information for anti-CHES1 antibody
This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms. [NCBI Entrez Gene Summary]

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
51,534 Da
NCBI Official Full Name
Homo sapiens forkhead box N3 (FOXN3), transcript variant 2, mRNA
NCBI Official Synonym Full Names
forkhead box N3
NCBI Official Symbol
FOXN3
NCBI Official Synonym Symbols
CHES1; PRO1635; C14orf116
NCBI Protein Information
forkhead box protein N3; checkpoint suppressor 1
UniProt Protein Name
Forkhead box protein N3
UniProt Gene Name
FOXN3
UniProt Entry Name
FOXN3_HUMAN

NCBI Description

This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

FOXN3: Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints). 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 14q31.3

Cellular Component: nucleus

Molecular Function: protein C-terminus binding; protein binding; sequence-specific DNA binding; transcription factor activity

Biological Process: transcription, DNA-dependent; mitotic cell cycle G2/M transition DNA damage checkpoint; negative regulation of transcription, DNA-dependent

Research Articles on CHES1

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Product Notes

The CHES1 foxn3 (Catalog #AAA120054) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse monoclonal antibody Anti-Human CHES1 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CHES1 can be used in a range of immunoassay formats including, but not limited to, Dot Blot (DB). Researchers should empirically determine the suitability of the CHES1 foxn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CHES1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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