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Western Blot (WB) (CDH11 monoclonal antibody (M04), clone 1A5. Western Blot analysis of CDH11 expression in human kidney.)

Mouse CDH11 Monoclonal Antibody | anti-CDH11 antibody

CDH11 (Cadherin 11, Type 2, OB-Cadherin (Osteoblast), CAD11, CDHOB, OB, OSF-4) (AP)

Gene Names
CDH11; OB; CAD11; CDHOB; OSF-4
Applications
ELISA, Immunoprecipitation, Western Blot
Purity
Purified
Synonyms
CDH11; Monoclonal Antibody; CDH11 (Cadherin 11; Type 2; OB-Cadherin (Osteoblast); CAD11; CDHOB; OB; OSF-4) (AP); Cadherin 11; OSF-4; anti-CDH11 antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG
Clone Number
1A5
Specificity
Recognizes CDH11.
Purity/Purification
Purified
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Applicable Applications for anti-CDH11 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
CDH11 (P55287, 54aa-612aa) partial recombinant protein with Fc tag at C terminal. MW of the Fc tag alone is 50kD.
Conjugate
AP
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(CDH11 monoclonal antibody (M04), clone 1A5. Western Blot analysis of CDH11 expression in human kidney.)

Western Blot (WB) (CDH11 monoclonal antibody (M04), clone 1A5. Western Blot analysis of CDH11 expression in human kidney.)

Immunoprecipitation (IP)

(Immunoprecipitation of full length CDH11 over expression in L cell using CDH11 monoclonal antibody (M03), clone 1A5, and immunoblotted with CDH11 monoclonal antibody (Zymed).)

Immunoprecipitation (IP) (Immunoprecipitation of full length CDH11 over expression in L cell using CDH11 monoclonal antibody (M03), clone 1A5, and immunoblotted with CDH11 monoclonal antibody (Zymed).)

Flow Cytometry (FC/FACS)

(FACS analysis of negative control PC3-MM2 cells only, mock control cells staining with 2nd antibodies and CDH11 stained PC3-MM2 cells.)

Flow Cytometry (FC/FACS) (FACS analysis of negative control PC3-MM2 cells only, mock control cells staining with 2nd antibodies and CDH11 stained PC3-MM2 cells.)

Western Blot (WB)

(CDH11 monoclonal antibody (M04), clone 1A5. Western Blot analysis of CDH11 expression in human ovarian cancer.)

Western Blot (WB) (CDH11 monoclonal antibody (M04), clone 1A5. Western Blot analysis of CDH11 expression in human ovarian cancer.)
Related Product Information for anti-CDH11 antibody
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq]
Product Categories/Family for anti-CDH11 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
87,965 Da
NCBI Official Full Name
cadherin-11 preproprotein
NCBI Official Synonym Full Names
cadherin 11, type 2, OB-cadherin (osteoblast)
NCBI Official Symbol
CDH11
NCBI Official Synonym Symbols
OB; CAD11; CDHOB; OSF-4
NCBI Protein Information
cadherin-11
UniProt Protein Name
Cadherin-11
Protein Family
UniProt Gene Name
CDH11
UniProt Synonym Gene Names
OB-cadherin
UniProt Entry Name
CAD11_HUMAN

NCBI Description

This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]

Uniprot Description

CDH11: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Interacts with PCDH8. Expressed mainly in brain but also found in other tissues. Expressed in neuroblasts. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Cell adhesion; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 16q21

Cellular Component: cytoplasm; integral to membrane; plasma membrane

Molecular Function: calcium ion binding

Biological Process: intercellular junction assembly and maintenance; ossification; corticospinal tract morphogenesis; homophilic cell adhesion; cell adhesion; skeletal development

Research Articles on CDH11

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Product Notes

The CDH11 cdh11 (Catalog #AAA6165528) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CDH11 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the CDH11 cdh11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDH11, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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