Western Blot (WB)
(Western blot analysis of Cdc37 on different lysates using anti-Cdc37 antibody at 1/1, 000 dilution. Positive control: Lane 1: Jurkat Lane 2: A431 Lane 3: K562)
Rabbit CDC37 Monoclonal Antibody | anti-CDC37 antibody
CDC37 Antibody
IHC: 1:50-1:200
FC/FACS: 1:50-1:100
Western Blot (WB)
(Western blot analysis of Cdc37 on different lysates using anti-Cdc37 antibody at 1/1, 000 dilution. Positive control: Lane 1: Jurkat Lane 2: A431 Lane 3: K562)
Western Blot (WB)
(Western blot analysis of Cdc37 on different lysates using anti-Cdc37 antibody at 1/1, 000 dilution. Positive control: Lane 1: Jurkat Lane 2: A431 Lane 3: K562)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-Cdc37 antibody. Counter stained with hematoxylin.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-Cdc37 antibody. Counter stained with hematoxylin.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded mouse placenta tissue using anti-Cdc37 antibody. Counter stained with hematoxylin.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded mouse placenta tissue using anti-Cdc37 antibody. Counter stained with hematoxylin.)
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of Hela cells with Cdc37 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody)
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of Hela cells with Cdc37 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008]
Uniprot Description
CDC37: a molecular chaperone that functions in cell signal transduction. Forms complexes with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. Also interacts with androgen receptor. It is thought to play a critical role in directing Hsp90 to its target kinases.
Protein type: Chaperone
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: protein complex; cytoplasm; cytosol
Molecular Function: protein kinase B binding; protein binding; heat shock protein binding; chaperone binding; unfolded protein binding; Hsp90 protein binding; mitogen-activated protein kinase kinase kinase binding; kinase binding
Biological Process: protein stabilization; protein folding; regulation of cyclin-dependent protein kinase activity; protein targeting
Research Articles on CDC37
Similar Products
Product Notes
The CDC37 cdc37 (Catalog #AAA9435981) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CDC37 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CDC37 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FC/FACS). WB: 1:1000-5000 IHC: 1:50-1:200 FC/FACS: 1:50-1:100. Researchers should empirically determine the suitability of the CDC37 cdc37 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDC37, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
