Testing Data
Rat anti-Mouse CD94 Monoclonal Antibody | anti-CD94 antibody
Anti-Mouse CD94, Purified, (clone: 15F.18D1), (rat IgG1k)
Gene Names
KLRD1; CD94
Reactivity
Mouse
Applications
Immunohistochemistry, ELISA, Immunofluorescence
Synonyms
CD94; Monoclonal Antibody; Anti-Mouse CD94; Purified; (clone: 15F.18D1); (rat IgG1k); Anti-Mouse CD94 Monoclonal Antibody; anti-CD94 antibody
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
Lewis Rat IgG1kappa
Clone Number
15F.18D1
Specificity
CD94 (Mouse CD94 transmembrane glycoprotein)
Form/Format
Purified
Concentration
1 mg/ml (varies by lot)
Sequence Length
54
Applicable Applications for anti-CD94 antibody
Immunohistochemistry (IHC), ELISA (EIA), Immunofluorescence (IF)
Immunogen
Murine T cell clone AE7 cells
Donor
Lewis Rat spleen cells
Fusion Partner
Murine myeloma cell line SP2/0
Presentation
Purified IgG buffered in PBS and 0.02% NaN3. (Purified from ascitic fluid via Protein G Chromatography).
Preparation and Storage
For all formats, store at 4 degree C. DO NOT FREEZE PE conjugates. For long term storage (Purified, Biotin, FITC, No Azide), aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
Testing Data
Testing Data
Related Product Information for anti-CD94 antibody
anti-mouse CD94 monoclonal antibody detects the mouse CD94 receptor. This 180 amino acid, 70 KDa transmembrane glycoprotein belongs to a family of murine Natural Killer (NK) cell receptors for MHC class I and is co-expressed as a heterodimer with NKG2 on the cellular surface. CD94 is expressed on NK cells as well as NK T cells. Both the murine CD94/NKG2 heterodimer and its human homologue are expressed on Th1 but not Th2 cells. Similar in function to the NKG2 family of receptors, CD94 is involved in NK target cell recognition, functions as an inhibitory receptor and plays an important role in adhesion and activation of the NK cell lineage. The unique expression of the CD94/NKG2 heterodimer on the Th1 subset of activated CD4+ cells suggests the potential use of our MBS520255 antibody in cell differentiation studies. This antibody has been reported to work in Flow Cytometry, ELISA and Immunofluorescence.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
20,513 Da
NCBI Official Full Name
CD94
NCBI Official Synonym Full Names
killer cell lectin-like receptor subfamily D, member 1
NCBI Official Symbol
KLRD1
NCBI Official Synonym Symbols
CD94
NCBI Protein Information
natural killer cells antigen CD94; KP43; CD94 antigen; NK cell receptor
UniProt Protein Name
Natural killer cells antigen CD94
UniProt Gene Name
KLRD1
UniProt Synonym Gene Names
CD94
UniProt Entry Name
KLRD1_HUMAN
NCBI Description
Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
Function: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
Subunit structure: Can form disulfide-bonded heterodimer with NKG2 family members. Ref.8 Ref.9 Ref.10
Subcellular location: Membrane; Single-pass type II membrane protein.
Tissue specificity: Natural killer cells.
Sequence similarities: Contains 1 C-type lectin domain.
Research Articles on CD94
Similar Products
Product Notes
The CD94 klrd1 (Catalog #AAA520255) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti-Mouse CD94, Purified, (clone: 15F.18D1), (rat IgG1k) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD94 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA), Immunofluorescence (IF). Researchers should empirically determine the suitability of the CD94 klrd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD94, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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