Mouse CD91, 85kD Monoclonal Antibody
CD91, 85kD (LRP, alpha2MR, Low Density Lipoprotein Receptor-related Protein)
Reactivity
Hamster, Human, Mouse, Rabbit, Rat
Applications
Western Blot, Immunohistochemistry, Flow Cytometry, Functional Assay, Immunofluorescence
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
CD91; 85kD; Monoclonal Antibody; 85kD (LRP; alpha2MR; Low Density Lipoprotein Receptor-related Protein); Anti -CD91; anti-CD91; 85kD antibody
Host
Mouse
Reactivity
Hamster, Human, Mouse, Rabbit, Rat
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
5F126
Specificity
Recognizes the 85kD b-chain of human CD91 (LRP/a2MR expressed in a restricted spectrum of cell types. Immunohistochemical reaction is seen in hepatocytes, tissue macrophages, subsets of neurons and astrocytes in the central nervous system, fibroblasts, smooth muscle cells and monocyte-derived foam cells in atherosclerotic lesions in the arterial wall. Species Crossreactivity: rabbit, rat, hamster and mouse.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a lyophilized powder from PBS, pH 7.4, 0.5% BSA. Reconstitute with 1ml sterile ddH2O.
Applicable Applications for anti-CD91, 85kD antibody
Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunofluorescence (IF)
Application Notes
Suitable for use in Immunofluorescence, Flow Cytometry, Immunohistochemistry and Western Blot.
Dilution: Immunohistochemistry: 1:20
Dilution: Immunohistochemistry: 1:20
Immunogen
Human CD41 (LRP/a2MR)
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-CD91, 85kD antibody
CD91, also known as a2-macroglobulin receptor (a2MR), apolipoprotein E receptor (ApoER) and low density lipoprotein receptor-related protein (LRP), is a large two-chain membrane protein that binds the proteinase-activated form of the plasma membrane protein a2M(1). a2M is a proteinase-inhibitor containing a region that is a substrate for a wide range of proteinases including trypsin, chymotrypsin, plasmin, neutrophil elastase and fibroblast collagenase(1). Binding of a2M:proteinase complexes to a2MR is followed by endocytosis and degradation of the ligand in lysosomes.
Product Categories/Family for anti-CD91, 85kD antibody
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Product Notes
The CD91, 85kD (Catalog #AAA606219) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD91, 85kD (LRP, alpha2MR, Low Density Lipoprotein Receptor-related Protein) reacts with Hamster, Human, Mouse, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD91, 85kD can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunofluorescence (IF). Suitable for use in Immunofluorescence, Flow Cytometry, Immunohistochemistry and Western Blot. Dilution: Immunohistochemistry: 1:20. Researchers should empirically determine the suitability of the CD91, 85kD for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD91, 85kD, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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