Rat anti-Mouse CD49e Monoclonal Antibody | anti-CD49e antibody
CD49e (VLA-5, Integrin alpha 5 Chain) (MaxLight 550)
Gene Names
Itga5; Fnra; VLA5; Cd49e
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry
Purity
Purified by protein G affinity chromatography from tissue culture supernatant.
Synonyms
CD49e; Monoclonal Antibody; CD49e (VLA-5; Integrin alpha 5 Chain) (MaxLight 550); anti-CD49e antibody
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
6A305
Specificity
Recognizes murine integrin alpha 5 (CD49e), which associates with the beta 1 integrin (CD29) to form the fibronectin receptor CD49e/CD29 (VLA-5).
Purity/Purification
Purified by protein G affinity chromatography from tissue culture supernatant.
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight550.
Sequence Length
1053
Applicable Applications for anti-CD49e antibody
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC)
Immunogen
Mouse MC/9 cell line.
Conjugate
MaxLight550
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Product Categories/Family for anti-CD49e antibody
References
1. Kinashi, T. and Springer, T. A. (1994) Adhesion Molecules in Hematopoietic cells. Blood cells. 20:25-44 2 Van der Loo, J. C. M. et al. (1998) VLA-5 Is Expressed by Mouse and Human Long-term Repopulating Hematopoietic Cells and Mediates Adhesion to Extracellular Matrix Protein Fibronectin. J. Clin. Invest. 102:1051-1061. 3. Cukierman, E. et al. (2001) Taking Cell-Matrix adhesions to the Third Dimension. Science. 294:1708-1712.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Integrin alpha-5
NCBI Official Synonym Full Names
integrin alpha 5 (fibronectin receptor alpha)
NCBI Official Symbol
Itga5
NCBI Official Synonym Symbols
Fnra; VLA5; Cd49e
NCBI Protein Information
integrin alpha-5
UniProt Protein Name
Integrin alpha-5
UniProt Gene Name
Itga5
UniProt Entry Name
ITA5_MOUSE
NCBI Description
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain, which is proteolytically processed to generate light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signaling. Integrin alpha 5 and integrin alpha V chains are produced by distinct genes. Homozygous knockout mice for this gene exhibit embryonic lethality. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Research Articles on CD49e
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Product Notes
The CD49e itga5 (Catalog #AAA6254681) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The CD49e (VLA-5, Integrin alpha 5 Chain) (MaxLight 550) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD49e can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the CD49e itga5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD49e, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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