Mouse CD44 Monoclonal Antibody | anti-CD44 antibody

MOUSE ANTI HORSE CD44:FITC

Cat. Num. AAA224468

• Applications: Flow Cytometry, Functional Assay
• Synonyms: CD44; Monoclonal Antibody; MOUSE ANTI HORSE CD44:FITC; anti-CD44 antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: CVS18
• Form/Format: FITC; Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
• Concentration: IgG concentration 0.1 mg/ml (varies by lot)
• Sequence Length: 359

• Applicable Applications for anti-CD44 antibody: Flow cytometry (FC/FACS)
• Application Notes: Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul.; Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/10
• Perservative Stabilisers: 0.09% Sodium Azide (NaN3); 1% Bovine Serum Albumin; Preparation
• Immunogen: Equine leucocytes; Fusion Partners
• Target Species: Horse
• Preparation and Storage: Store at 4 degree C for one month or at -20 degree C for longer. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.; Shelf Life: 18 months from date of despatch.

Testing Data #1

(Staining of equine peripheral blood lymphocytes with Mouse anti Equine CD44 (MBS224573), followed by Goat anti Mouse IgG:FITC (MBS235142))

Testing Data #2

(Staining of equine peripheral blood lymphocytes with Mouse anti Equine CD44:FITC(MBS224468))

Testing Data #3

(Staining of equine peripheral blood lymphocytes with Mouse anti Equine CD44:FITC(MBS224468))

Related Product Information for anti-CD44 antibody

Mouse anti Horse CD11a/CD18 antibody, clone CVS9 recognizes equine CD44, a plasma membrane glycoprotein broadly expressed on the cell surface of leucocytes. CD44 is the primary receptor for hyaluronate and functions in cell adhesion. Equine CD44 is widely expressed and Mouse anti Horse CD11a/CD18 antibody, clone CVS9 may be used as a pan equine leucocyte marker.

NCBI and Uniprot Product Information

• NCBI GI #: 146198854
• NCBI GeneID: 100034221
• NCBI Accession #: NP_001078904.1
• NCBI GenBank Nucleotide #: NM_001085435.1
• UniProt Accession #: Q05078
• Molecular Weight: 38,990 Da
• NCBI Official Full Name: CD44 antigen
• NCBI Official Symbol: CD44
• NCBI Protein Information: CD44 antigen; CD44 antigen-like protein; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; PGP-1; PGP-I; extracellular matrix receptor III; hermes antigen; hyaluronate receptor; lymphocyte surface antigen precursor CD44; phagocytic glycoprotein 1; phagocytic glycoprotein I
• UniProt Protein Name: CD44 antigen
• Protein Family: CD44 antigen
• UniProt Gene Name: CD44
• UniProt Synonym Gene Names: ECMR-III; PGP-1; PGP-I
• UniProt Entry Name: CD44_HORSE

Uniprot Description

Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Receptor for LGALS9; the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function.