Flow Cytometry (FC/FACS)
(Figure 1: Cell surface staining of rat splenocytes. Green represents FITC conjugated isotope control. Red represents FITC conjugated Anti-rat CD43 antibody. 0.2 ug antibody was used.)
Mouse anti-Rat CD43 Monoclonal Antibody | anti-CD43 antibody
Monoclonal Antibody to Rat CD43 (Clone:WEN3) FITC Conjugated
IHC: 5-10 ug
Flow Cytometry (FC/FACS)
(Figure 1: Cell surface staining of rat splenocytes. Green represents FITC conjugated isotope control. Red represents FITC conjugated Anti-rat CD43 antibody. 0.2 ug antibody was used.)
Flow Cytometry (FC/FACS)
(Figure 1: Cell surface staining of rat splenocytes. Green represents FITC conjugated isotope control. Red represents FITC conjugated Anti-rat CD43 antibody. 0.2 ug antibody was used.)
NCBI and Uniprot Product Information
NCBI Description
major glycoprotein of thymocytes and T lymphocytes [RGD, Feb 2006]
Uniprot Description
Predominant cell surface sialoprotein of leukocytes which regulates multiple T-cell functions, including T-cell activation, proliferation, differentiation, trafficking and migration. Positively regulates T-cell trafficking to lymph-nodes via its association with ERM proteins (EZR, RDX and MSN). Negatively regulates Th2 cell differentiation and predisposes the differentiation of T-cells towards a Th1 lineage commitment. Promotes the expression of IFN-gamma by T-cells during T-cell receptor (TCR) activation of naive cells and induces the expression of IFN-gamma by CD4+ T-cells and to a lesser extent by CD8+ T-cells. Plays a role in preparing T-cells for cytokine sensing and differentiation into effector cells by inducing the expression of cytokine receptors IFNGR and IL4R, promoting IFNGR and IL4R signaling and by mediating the clustering of IFNGR with TCR. Acts as a major E-selectin ligand responsible for Th17 cell rolling on activated vasculature and recruitment during inflammation. Mediates Th17 cells, but not Th1 cells, adhesion to E-selectin. Acts as a T-cell counter-receptor for SIGLEC1.
Research Articles on CD43
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Product Notes
The CD43 spn (Catalog #AAA669243) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Monoclonal Antibody to Rat CD43 (Clone:WEN3) FITC Conjugated reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD43 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). FC/FACS: 0.2-05 ug/10^6 Cells IHC: 5-10 ug. Researchers should empirically determine the suitability of the CD43 spn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD43, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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