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Hamster anti-Mouse CD31 Monoclonal Antibody | anti-CD31 antibody

CD31 (PECAM-1, Platelet gpIIa Molecule) (AP)

Gene Names
Pecam1; Cd31; Pecam; C85791; PECAM-1
Reactivity
Mouse
Purity
Purified
Synonyms
CD31; Monoclonal Antibody; CD31 (PECAM-1; Platelet gpIIa Molecule) (AP); anti-CD31 antibody
Ordering
For Research Use Only!
Host
Hamster
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG
Clone Number
2Q682
Specificity
Recognizes the 130-140kD protein, PECAM-1 found on mouse monocytes, platelets, granulocytes and endothelial cells. Effectively inhibits transmigration of activated polymorphonuclear cells and monocytes across the endothelium. In a mouse model for acute peritonis, blocks acute inflammation
Purity/Purification
Purified
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase.
Immunogen
CD31 (PECAM-1).
Conjugate
AP
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Product Categories/Family for anti-CD31 antibody
References
1. Yong, X., et al., Proc. Natl. Acad. Sci. 90: 5569-5573 (1993). 2. Bogen, S., et al., J. Exp. Med. 179: 1059-1064 (1994). 3. Newman, P.J., et al., J. Cell. Biol. 119: 239-246 (1992).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
69,823 Da
NCBI Official Full Name
Platelet endothelial cell adhesion molecule
NCBI Official Synonym Full Names
platelet/endothelial cell adhesion molecule 1
NCBI Official Symbol
Pecam1
NCBI Official Synonym Symbols
Cd31; Pecam; C85791; PECAM-1
NCBI Protein Information
platelet endothelial cell adhesion molecule; PECAM-1/CD31
UniProt Protein Name
Platelet endothelial cell adhesion molecule
UniProt Gene Name
Pecam1
UniProt Synonym Gene Names
Pecam; Pecam-1; PECAM-1
UniProt Entry Name
PECA1_MOUSE

Uniprot Description

PECAM-1: a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.

Protein type: Cell adhesion; Membrane protein, integral

Cellular Component: extracellular space; cell surface; smooth muscle contractile fiber; membrane; integral to membrane; plasma membrane; intracellular; cell junction; lipid raft; external side of plasma membrane

Molecular Function: protein binding

Biological Process: negative regulation of peptidyl-tyrosine phosphorylation; wound healing; positive regulation of tyrosine phosphorylation of Stat5 protein; negative regulation of actin filament polymerization; positive regulation of leukocyte migration; diapedesis; cell adhesion; regulation of cell migration; phagocytosis; Rho protein signal transduction

Research Articles on CD31

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Product Notes

The CD31 pecam1 (Catalog #AAA6241598) is an Antibody produced from Hamster and is intended for research purposes only. The product is available for immediate purchase. The CD31 (PECAM-1, Platelet gpIIa Molecule) (AP) reacts with Mouse and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "CD31, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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