Flow Cytometry (FC/FACS)
(Flow cytometric analysis of Human CD31 expression. Profile of human whole blood monocytes (left panel) and granulocyte (right panel) analyzed on a FACSCalibur (BDIS, San Jose, CA). The histogram were derived from the gated events based on light scattering characteristics of monocytes and granulocytes.)
Mouse anti-Human CD31 Monoclonal Antibody | anti-PECAM1 antibody
Anti-CD31 Antibody (APC), Mouse Monoclonal
Gene Names
PECAM1; CD31; PECA1; GPIIA'; PECAM-1; endoCAM; CD31/EndoCAM
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Purity
Protein A
Synonyms
CD31; Monoclonal Antibody; Anti-CD31 Antibody (APC); Mouse Monoclonal; CD31/PECAM1 Antibody (APC); Mouse MAb; platelet/endothelial cell adhesion molecule 1; Anti-CD31 Antibody; Anti-CD31/EndoCAM Antibody; Anti-endoCAM Antibody; Anti-GPIIA' Antibody; Anti-PECA1 Antibody; Anti-PECAM-1 Antibody; anti-PECAM1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse IgG1
Clone Number
13
Specificity
Human CD31/PECAM1
Purity/Purification
Protein A
Form/Format
Liquid; Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Concentration
5ul/Test, 0.1mg/ml (varies by lot)
Applicable Applications for anti-PECAM1 antibody
Flow Cytometry (FC/FACS/FCM)
Immunogen
Recombinant Human CD31/PECAM1 protein
Conjugation
APC
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD31/PECAM1 (rh CD31/PECAM1) and conjugated with APC under optimum conditions, the unreacted APC was removed.
Preparation and Storage
This antibody can be stored at 2-8 degree C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of Human CD31 expression. Profile of human whole blood monocytes (left panel) and granulocyte (right panel) analyzed on a FACSCalibur (BDIS, San Jose, CA). The histogram were derived from the gated events based on light scattering characteristics of monocytes and granulocytes.)
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of Human CD31 expression. Profile of human whole blood monocytes (left panel) and granulocyte (right panel) analyzed on a FACSCalibur (BDIS, San Jose, CA). The histogram were derived from the gated events based on light scattering characteristics of monocytes and granulocytes.)
Related Product Information for anti-PECAM1 antibody
The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin alphavbeta3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development.
Product Categories/Family for anti-PECAM1 antibody
References
Deaglio S, et al. (2000) CD38/CD31, a receptor/ligand system ruling adhesion and signaling in human leukocytes. Chem Immunol. 75: 99-120.Kohler S, et al. (2009) Life after the thymus: CD31+ and CD31-human naive CD4+ T-cell subsets. Blood. 113(4): 769-74.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
81,378 Da
NCBI Official Full Name
platelet/endothelial cell adhesion molecule (CD31 antigen), isoform CRA_a
NCBI Official Synonym Full Names
platelet and endothelial cell adhesion molecule 1
NCBI Official Symbol
PECAM1
NCBI Official Synonym Symbols
CD31; PECA1; GPIIA'; PECAM-1; endoCAM; CD31/EndoCAM
NCBI Protein Information
platelet endothelial cell adhesion molecule
Protein Family
NCBI Description
The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010]
Research Articles on PECAM1
Similar Products
Product Notes
The PECAM1 (Catalog #AAA8101286) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-CD31 Antibody (APC), Mouse Monoclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD31 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS/FCM). Researchers should empirically determine the suitability of the PECAM1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD31, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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