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Flow Cytometry (FC/FACS) (Flow cytometric analysis of Mouse PECAM1(CD31) expression on BABL/c splenocytes. Cells were stained with FITC-conjugated anti-Mouse PECAM1(CD31). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.)

Rabbit anti-Mouse CD31 Monoclonal Antibody | anti-PECAM1 antibody

Recombinant Anti-CD31 Antibody (FITC), Rabbit Monoclonal

Gene Names
Bche; C730038G20Rik
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay
Purity
Protein A
Synonyms
CD31; Monoclonal Antibody; Recombinant Anti-CD31 Antibody (FITC); Rabbit Monoclonal; CD31/PECAM-1 Antibody (FITC); Rabbit MAb; platelet/endothelial cell adhesion molecule 1; Anti-C85791 Antibody; Anti-Cd31 Antibody; Anti-Pecam Antibody; Anti-PECAM-1 Antibody; anti-PECAM1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
008
Specificity
Mouse CD31/PECAM-1
Purity/Purification
Protein A
Form/Format
Liquid; Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Concentration
5ul/Test, 0.1mg/ml (varies by lot)
Applicable Applications for anti-PECAM1 antibody
Flow Cytometry (FC/FACS/FCM)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant Mouse CD31/PECAM-1 Protein
Conjugation
FITC
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD31/PECAM-1 (rM CD31/PECAM-1) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Preparation and Storage
This antibody can be stored at 2-8 degree C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Flow Cytometry (FC/FACS)

(Flow cytometric analysis of Mouse PECAM1(CD31) expression on BABL/c splenocytes. Cells were stained with FITC-conjugated anti-Mouse PECAM1(CD31). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.)

Flow Cytometry (FC/FACS) (Flow cytometric analysis of Mouse PECAM1(CD31) expression on BABL/c splenocytes. Cells were stained with FITC-conjugated anti-Mouse PECAM1(CD31). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.)
Related Product Information for anti-PECAM1 antibody
The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin alphavbeta3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development.
Product Categories/Family for anti-PECAM1 antibody
References
Deaglio S, et al. (2000) CD38/CD31, a receptor/ligand system ruling adhesion and signaling in human leukocytes. Chem Immunol. 75: 99-120.Kohler S, et al. (2009) Life after the thymus: CD31+ and CD31-human naive CD4+ T-cell subsets. Blood. 113(4): 769-74.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
68,462 Da
NCBI Official Full Name
cholinesterase
NCBI Official Synonym Full Names
butyrylcholinesterase
NCBI Official Symbol
Bche
NCBI Official Synonym Symbols
C730038G20Rik
NCBI Protein Information
cholinesterase
UniProt Protein Name
Cholinesterase
UniProt Gene Name
Bche
UniProt Entry Name
CHLE_MOUSE

Uniprot Description

BCHE: Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters. Defects in BCHE are the cause of butyrylcholinesterase deficiency (BChE deficiency). BChE deficiency is a metabolic disorder characterized by prolonged apnoea after the use of certain anesthetic drugs, including the muscle relaxants succinylcholine or mivacurium and other ester local anesthetics. The duration of the prolonged apnoea varies significantly depending on the extent of the enzyme deficiency. BChE deficiency is a multifactorial disorder. The hereditary condition is transmitted as an autosomal recessive trait. Belongs to the type-B carboxylesterase/lipase family.

Protein type: Hydrolase; Nuclear envelope; Secreted; EC 3.1.1.8; Secreted, signal peptide

Cellular Component: endoplasmic reticulum; endoplasmic reticulum lumen; extracellular region; extracellular space; membrane; nuclear envelope lumen

Molecular Function: 1-oxa-2-oxocycloheptane lactonase activity; 3,4-dihydrocoumarin hydrolase activity; acetylcholinesterase activity; all-trans-retinyl-palmitate hydrolase activity; butyrolactone hydrolase activity; choline binding; cholinesterase activity; hydrolase activity; identical protein binding; lipase activity; phospholipase activity; prenylcysteine methylesterase activity; retinyl-palmitate esterase activity; sulfolactone hydrolase activity

Biological Process: choline metabolic process; learning; negative regulation of cell proliferation; negative regulation of synaptic transmission; neuroblast differentiation; response to alkaloid; response to drug; response to folic acid; response to glucocorticoid stimulus; response to nutrient

Research Articles on PECAM1

Similar Products

Product Notes

The PECAM1 bche (Catalog #AAA8111521) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Anti-CD31 Antibody (FITC), Rabbit Monoclonal reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD31 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS/FCM). Researchers should empirically determine the suitability of the PECAM1 bche for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD31, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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