Dilution Information
Rabbit anti-Human CD3 Epsilon Monoclonal Antibody | anti-CD3 Epsilon antibody
CD3 Epsilon RMab
Reactivity
Human
Synonyms
CD3 Epsilon; Monoclonal Antibody; CD3 Epsilon RMab; anti-CD3 Epsilon antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Clone Number
RBT-CD3e
Form/Format
CD3 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Control
Tonsil, Lymph Node
Localization
Membranous
Reactivity Note
Paraffin, Frozen
Preparation and Storage
Store at 2 to 8 degree C in the dark.
Dilution Information
Dilution Information
Immunohistochemistry (IHC)
Immunohistochemistry (IHC)
Related Product Information for anti-CD3 Epsilon antibody
The CD3 antigen is a protein complex composed of three distinct chains (CD3gamma, CD3delta and CD3epsilon) that associate with T-cell receptors and the zeta-chain to generate an activation signal in T-lymphocytes. The TCR, zeta-chain and CD3 molecules together comprise the TCR complex. The CD3gamma, CD3delta and CD3epsilon chains are highly-related cell surface proteins of the immunoglobulin superfamily containing a single extracellular immunoglobulin domain. The intracellular tails of the CD3 molecules contain a single conserved motif known as an immunoreceptor tyrosine-based activation motif (or ITAM for short), which is essential for the signaling capacity of the TCR. Phosphorylation of the ITAM on CD3 renders the CD3 chain capable of binding the enzyme ZAP70 (zeta-associated protein), a kinase important in the signaling cascade of the T-cell.The CD3 has been considered the best all-around T-cell marker. This antibody reacts with an antigen present in early thymocytes. The positive staining of this marker may represent a sign of early commitment to the T-cell lineage.
NCBI and Uniprot Product Information
Similar Products
Product Notes
The CD3 Epsilon cd3g (Catalog #AAA370024) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD3 Epsilon RMab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "CD3 Epsilon, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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