Rat anti-Mouse CD3 Monoclonal Antibody | anti-CD3 antibody
CD3 (Early T Cell Marker, T Cell receptor Complex, TCR) (MaxLight 490)
Gene Names
Cd3e; CD3; T3e; AI504783; CD3epsilon
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry
Purity
Purified by protein G affinity chromatography from tissue culture supernatant.
Synonyms
CD3; Monoclonal Antibody; CD3 (Early T Cell Marker; T Cell receptor Complex; TCR) (MaxLight 490); anti-CD3 antibody
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
3H698
Specificity
Recognizes the mouse CD3 antigen, which is expressed by mature T cells. The antibody may be used to trigger proliferation and cytotoxicity of CD3 positive cells. For optimal staining incubations should be performed at room temperature.
Purity/Purification
Purified by protein G affinity chromatography from tissue culture supernatant.
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight490.
Applicable Applications for anti-CD3 antibody
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC)
Conjugate
MaxLight490
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Product Categories/Family for anti-CD3 antibody
References
1. Tomonari, K., Immunogenetics 28: 455-458 (1988). 2. Lacroix-Lamandé, S., et al., Infect. Immun. 70(4): 2090-2099 (2002). 3. Tomonari, K., Immunogenetics 28: 445-451 (1988). 3. Tomonari, K. (1988) Immunogenetics 28: 445-451. 4. Haroon, F. et al., (2011) J Immunol. 186: 6521-31. 5. Kumar, L. et al. (2002) Proc Natl Acad Sci U S A. 99: 884-9. 6. Hirsh, M. et al. (2004) Immunology. 112: 153-60. 7. Tarlton, J.F. et al. (2000) Am J Pathol. 157: 1927-35. 8. Lazarovits, A.I. et al. (1999) Kidney Int. 55: 1303-10. 9. Bauer, D. et al. (2009) Invest Ophthalmol Vis Sci. 50: 3188-98. 10. Heitmann, S. et al. (1999) Lab Anim. 33: 288-94. 11. Hare, K.J. et al. (2003) J Immunol. 171: 2825-31. 12. Erlandsson, L. et al. (2004) Eur J Immunol. 34: 3595-603. 13. Severinova, J. et al. (2005) Folia Microbiol (Praha). 50: 457-63.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21,393 Da
NCBI Official Full Name
T-cell surface glycoprotein CD3 epsilon chain
NCBI Official Synonym Full Names
CD3 antigen, epsilon polypeptide
NCBI Official Symbol
Cd3e
NCBI Official Synonym Symbols
CD3; T3e; AI504783; CD3epsilon
NCBI Protein Information
T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain
UniProt Protein Name
T-cell surface glycoprotein CD3 epsilon chain
Protein Family
UniProt Gene Name
Cd3e
UniProt Entry Name
CD3E_MOUSE
Research Articles on CD3
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Product Notes
The CD3 cd3e (Catalog #AAA6253529) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The CD3 (Early T Cell Marker, T Cell receptor Complex, TCR) (MaxLight 490) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD3 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the CD3 cd3e for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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