Testing Data
Mouse anti-Rat CD28 Monoclonal Antibody | anti-CD28 antibody
Anti-Rat CD28 Biotin (Clone JJ319) (mouse IgG1)
Reactivity
Rat
Applications
Immunohistochemistry
Synonyms
CD28; Monoclonal Antibody; Anti-Rat CD28 Biotin (Clone JJ319) (mouse IgG1); CD28 Biotin (Clone JJ319) (mouse IgG1); Biotin Anti-Rat CD28 Monoclonal Antibody; anti-CD28 antibody
Host
Mouse
Reactivity
Rat
Clonality
Monoclonal
Isotype
Mouse IgG1
Clone Number
JJ319
Specificity
CD28 (Tp44; receptor for B7 family) (Rat CD28)
Form/Format
Biotin (Biotin conjugated Ig buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml. (Purified from Bioreactor supernatant via Protein G Chromatography))
Concentration
Antibody Concentration: 0.1 mg/ml (varies by lot)
Sequence Length
221
Applicable Applications for anti-CD28 antibody
Immunohistochemistry (IHC)
Immunogen
Rat CD28 transfected A20J cells
Donor
BALB/c spleen
Fusion Partner
X63-Ag 8.653
Presentation
100 ug or 500 ug Biotin conjugated Ig buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.
Preparation and Storage
Store at 4 degree C. For long term storage, aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
Testing Data
Testing Data
Related Product Information for anti-CD28 antibody
anti-rat CD28 monoclonal antibody recognizes a 90kDa homeodimeric cell surface glycoprotein. CD28 has been found to be a potent costimulatory receptor on T cells. It is expressed on all peripheral rat ab and most gd T cells, as well as on approximately half of all NK cells. This clone can costimulate T cell proliferation and IL-2 secretion by resting rat T cells. Applications: Flow cytometry
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
25,307 Da
NCBI Official Full Name
T-cell-specific surface glycoprotein CD28
NCBI Official Symbol
CD28
NCBI Protein Information
T-cell-specific surface glycoprotein CD28
UniProt Protein Name
T-cell-specific surface glycoprotein CD28
Protein Family
UniProt Gene Name
CD28
UniProt Entry Name
CD28_RABIT
Uniprot Description
Function: Possibly involved in T-cell activation
By similarity.
Subunit structure: Homodimer; disulfide-linked. Interacts with DUSP14. Binds to CD80/B7-1 and CD86/B7-2/B70
By similarity.
Subcellular location: Membrane; Single-pass type I membrane protein.
Sequence similarities: Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Similar Products
Product Notes
The CD28 cd28 (Catalog #AAA520090) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Rat CD28 Biotin (Clone JJ319) (mouse IgG1) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD28 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the CD28 cd28 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD28, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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