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Testing Data (Staining of mouse peripheral blood lymphocytes with RAT ANTI MOUSE CD26)

Rat anti-Mouse CD26 Monoclonal Antibody | anti-CD26 antibody

CD26 (ADABP, ADCP2, Adenosine Deaminase Complexing Protein 2, Dipeptidyl Peptidase IV, Dipeptidylpeptidase 4, DPP4, DPPIV, Intestinal Dipeptidyl Peptidase, T cell Activation Antigen CD26, TP103) (HRP)

Gene Names
Dpp4; Cd26; THAM; Dpp-4
Reactivity
Mouse
Applications
ELISA, Flow Cytometry, Functional Assay
Purity
Purified by protein G affinity chromatography from tissue culture supernatant.
Synonyms
CD26; Monoclonal Antibody; CD26 (ADABP; ADCP2; Adenosine Deaminase Complexing Protein 2; Dipeptidyl Peptidase IV; Dipeptidylpeptidase 4; DPP4; DPPIV; Intestinal Dipeptidyl Peptidase; T cell Activation Antigen CD26; TP103) (HRP); anti-CD26 antibody
Ordering
For Research Use Only!
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
10B1155
Specificity
Recognizes mouse CD26.
Purity/Purification
Purified by protein G affinity chromatography from tissue culture supernatant.
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with horseradish peroxidase (HRP).
Applicable Applications for anti-CD26 antibody
ELISA (EIA), Flow Cytometry (FC/FACS)
Conjugate
HRP
Preparation and Storage
Store at -20 degree C.

Testing Data

(Staining of mouse peripheral blood lymphocytes with RAT ANTI MOUSE CD26)

Testing Data (Staining of mouse peripheral blood lymphocytes with RAT ANTI MOUSE CD26)

Testing Data

(Staining of mouse peripheral blood lymphocytes with RAT ANTI MOUSE CD26)

Testing Data (Staining of mouse peripheral blood lymphocytes with RAT ANTI MOUSE CD26)

Testing Data

(Staining of mouse peripheral blood lymphocytes with RAT ANTI MOUSE CD26:Alexa Fluor® 488)

Testing Data (Staining of mouse peripheral blood lymphocytes with RAT ANTI MOUSE CD26:Alexa Fluor® 488)

Testing Data

(Staining of mouse peripheral blood lymphocytes with RAT ANTI MOUSE CD26:Biotin)

Testing Data (Staining of mouse peripheral blood lymphocytes with RAT ANTI MOUSE CD26:Biotin)

Testing Data

(Staining of mouse peripheral blood lymphocytes with RAT ANTI MOUSE CD26:FITC)

Testing Data (Staining of mouse peripheral blood lymphocytes with RAT ANTI MOUSE CD26:FITC)
Product Categories/Family for anti-CD26 antibody
References
1. Vivier, I. et al. (1991) Evidence that thymocyte-activating molecule is mouse CD26 (dipeptidyl peptidase IV). J. Immunol. 147:447-54.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
87,437 Da
NCBI Official Full Name
Dipeptidyl peptidase 4
NCBI Official Synonym Full Names
dipeptidylpeptidase 4
NCBI Official Symbol
Dpp4
NCBI Official Synonym Symbols
Cd26; THAM; Dpp-4
NCBI Protein Information
dipeptidyl peptidase 4; DPP IV; dipeptidyl peptidase IV; thymocyte-activating molecule; T-cell activation antigen CD26
UniProt Protein Name
Dipeptidyl peptidase 4
UniProt Gene Name
Dpp4
UniProt Synonym Gene Names
Cd26; DPP IV; THAM
UniProt Entry Name
DPP4_MOUSE

Uniprot Description

DPP4: Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF- kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline. Belongs to the peptidase S9B family. DPPIV subfamily.

Protein type: Membrane protein, integral; Cell adhesion; EC 3.4.14.5; Cell surface; Protease

Cellular Component: Golgi apparatus; intercellular canaliculus; focal adhesion; cell surface; endoplasmic reticulum; lysosomal membrane; extracellular region; integral to membrane; cell projection; membrane; endocytic vesicle; lamellipodium; apical plasma membrane; plasma membrane; cell junction

Molecular Function: peptidase activity; collagen binding; identical protein binding; protein homodimerization activity; protease binding; hydrolase activity; serine-type peptidase activity; dipeptidyl-peptidase activity; serine-type endopeptidase activity; aminopeptidase activity; peptide binding; receptor binding

Biological Process: regulation of cell-cell adhesion mediated by integrin; behavioral fear response; T cell activation; establishment of localization; regulation of T cell mediated immunity; positive regulation of cell proliferation; T cell costimulation; response to hypoxia; endothelial cell migration; proteolysis; cell adhesion

Research Articles on CD26

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Product Notes

The CD26 dpp4 (Catalog #AAA6250504) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The CD26 (ADABP, ADCP2, Adenosine Deaminase Complexing Protein 2, Dipeptidyl Peptidase IV, Dipeptidylpeptidase 4, DPP4, DPPIV, Intestinal Dipeptidyl Peptidase, T cell Activation Antigen CD26, TP103) (HRP) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD26 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the CD26 dpp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD26, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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