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Western Blot (WB) (Western Blot analysis of recombinant human endostatin (50ng) was added to 3T3 cell lysate and probed with MBS600066 (1:1000).)

Mouse anti-Human, Mouse Endostatin Monoclonal Antibody | anti-Col18a1 antibody

Endostatin (MaxLight 650)

Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Thiophilic Chromatography.
Synonyms
Endostatin; Monoclonal Antibody; Endostatin (MaxLight 650); anti-Col18a1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Isotype
IgG
Clone Number
4i37
Specificity
Recognizes mouse Endostatin, Mr 22kD, an unidentified protein is also weakly detected, Mr 54kD. Species Crossreactivity: human
Purity/Purification
Purified by Thiophilic Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.
Applicable Applications for anti-Col18a1 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Immunogen
Full-length recombinant mouse Endostatin. Species Sequence Homology: rat.
Conjugate
MaxLight650
Preparation and Storage
Store at 4 degree C. Do Not Freeze.

Western Blot (WB)

(Western Blot analysis of recombinant human endostatin (50ng) was added to 3T3 cell lysate and probed with MBS600066 (1:1000).)

Western Blot (WB) (Western Blot analysis of recombinant human endostatin (50ng) was added to 3T3 cell lysate and probed with MBS600066 (1:1000).)
Product Categories/Family for anti-Col18a1 antibody
References
1. Sauter, B.V., et al., (2000) Proc. Natl. Acad. Sci. USA 97:4802-4807. 2. Dhanabal, M., et al., (1999) J. Biol. Chem. 274:11,721-11,726.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
134,204 Da
NCBI Official Full Name
collagen alpha-1(XVIII) chain isoform 1
NCBI Official Synonym Full Names
collagen, type XVIII, alpha 1
NCBI Official Symbol
Col18a1
NCBI Protein Information
collagen alpha-1(XVIII) chain; collagen alpha-1(XVIII) chain; endostatin; procollagen, type XVIII, alpha 1
UniProt Protein Name
Collagen alpha-1(XVIII) chain
Protein Family
UniProt Gene Name
Col18a1
UniProt Entry Name
COIA1_MOUSE

Uniprot Description

COL18A1: COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube. Defects in COL18A1 are a cause of Knobloch syndrome type 1 (KNO1). An autosomal recessive disorder defined by the occurrence of high myopia, vitreoretinal degeneration with retinal detachment, macular abnormalities and occipital encephalocele. Belongs to the multiplexin collagen family. 3 isoforms of the human protein are produced by alternative promoter.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular space; collagen; extracellular region; basement membrane

Molecular Function: identical protein binding; metal ion binding; structural molecule activity

Biological Process: extracellular matrix organization and biogenesis; positive regulation of cell proliferation; endothelial cell morphogenesis; angiogenesis; cell adhesion; positive regulation of cell migration

Research Articles on Col18a1

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Product Notes

The Col18a1 col18a1 (Catalog #AAA6246622) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Endostatin (MaxLight 650) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Endostatin can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the Col18a1 col18a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Endostatin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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