Flow Cytometry (FC/FACS)
(Human peripheral blood lymphocytes are stained with Anti-Human CD4 Monoclonal Antibody(APC Conjugated) and Anti-Human CD25 Monoclonal Antibody(PE/Cyanine7 Conjugated)(Left).lymphocytes stained with Anti-Human CD4 Monoclonal Antibody(APC Conjugated) and Mouse IgG1 Isotype Control PE/Cy7(Right) are used as control.)
Mouse anti-Human CD25 Monoclonal Antibody | anti-CD25 antibody
Anti-Human CD25 Monoclonal Antibody (PE/Cyanine7 Conjugated) [BC96]
Flow Cytometry (FC/FACS)
(Human peripheral blood lymphocytes are stained with Anti-Human CD4 Monoclonal Antibody(APC Conjugated) and Anti-Human CD25 Monoclonal Antibody(PE/Cyanine7 Conjugated)(Left).lymphocytes stained with Anti-Human CD4 Monoclonal Antibody(APC Conjugated) and Mouse IgG1 Isotype Control PE/Cy7(Right) are used as control.)
Flow Cytometry (FC/FACS)
(Human peripheral blood lymphocytes are stained with Anti-Human CD4 Monoclonal Antibody(APC Conjugated) and Anti-Human CD25 Monoclonal Antibody(PE/Cyanine7 Conjugated)(Left).lymphocytes stained with Anti-Human CD4 Monoclonal Antibody(APC Conjugated) and Mouse IgG1 Isotype Control PE/Cy7(Right) are used as control.)
NCBI and Uniprot Product Information
NCBI Description
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
Uniprot Description
IL2RA: Receptor for interleukin-2. Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 10p15-p14
Cellular Component: integral to membrane; plasma membrane; external side of plasma membrane
Molecular Function: interleukin-2 receptor activity; drug binding; interleukin-2 binding
Biological Process: Notch signaling pathway; regulation of T cell homeostatic proliferation; apoptosis; negative regulation of immune response; negative regulation of defense response to virus; positive regulation of activated T cell proliferation; cell proliferation; negative regulation of T cell proliferation; inflammatory response to antigenic stimulus; cell surface receptor linked signal transduction; positive regulation of T cell differentiation; negative regulation of inflammatory response; immune response; inflammatory response; activated T cell apoptosis
Disease: Interleukin 2 Receptor, Alpha, Deficiency Of; Diabetes Mellitus, Insulin-dependent, 10
Research Articles on CD25
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Product Notes
The CD25 il2ra (Catalog #AAA2559428) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Human CD25 Monoclonal Antibody (PE/Cyanine7 Conjugated) [BC96] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD25 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 2 muL or 5 muL of antibody per test (million cells in 100 ul staining volume or per 100 ul of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. Researchers should empirically determine the suitability of the CD25 il2ra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD25, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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