Flow Cytometry (FC/FACS)
(Mouse abdominal macrophages elicited by starch broth are stained with PE/Cyanine7 Anti-Mouse CD206 Antibody(filled gray histogram). Unstained macrophages (blank black histogram) are used as control.)
Rat anti-Mouse CD206 Monoclonal Antibody | anti-CD206 antibody
PE/Cyanine7 Anti-Mouse CD206 Antibody [C068C2]
Gene Names
Mrc1; MR; CD206; AW259686
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay
Synonyms
CD206; Monoclonal Antibody; PE/Cyanine7 Anti-Mouse CD206 Antibody [C068C2]; MMR; MR; MRC1; macrophage mannose receptor; mannose receptor; anti-CD206 antibody
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
Rat IgG2a, kappa
Clone Number
C068C2
Form/Format
PBS with 0.05% Proclin300, 1% BSA
Applicable Applications for anti-CD206 antibody
ICFlow Cytometry (FC/FACS/FCM)
Conjugation
PE/Cyanine7
Preparation and Storage
Store at 2~8 degree C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry (FC/FACS)
(Mouse abdominal macrophages elicited by starch broth are stained with PE/Cyanine7 Anti-Mouse CD206 Antibody(filled gray histogram). Unstained macrophages (blank black histogram) are used as control.)
Flow Cytometry (FC/FACS)
(Mouse abdominal macrophages elicited by starch broth are stained with PE/Cyanine7 Anti-Mouse CD206 Antibody(filled gray histogram). Unstained macrophages (blank black histogram) are used as control.)
Related Product Information for anti-CD206 antibody
CD206, also known as mannose receptor (MR), is a 175 kD type I membrane protein. It is a pattern recognition receptor (PRR) belonging to the C-type lectin superfamily. MR is expressed on macrophages, dendritic cells, Langerhans cells, and hepatic or lymphatic endothelial cells. MR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine through its C-type lectin-like carbohydrate recognition domains, sulfated carbohydrate antigens through its cysteine-rich domain, and collagens through its fibronectin type II domain. MR mediates endocytosis and phagocytosis as well as activation of macrophages and antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity. Recently, MR on lymphatic endothelial cells was found to be involved in leukocyte trafficking and a contributor to the metastatic behavior of cancer cells. It suggests that MR may be a potential target in controlling inflammation and cancer metastasis by targeting the lymphatic vasculature.
Product Categories/Family for anti-CD206 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
macrophage mannose receptor 1
NCBI Official Synonym Full Names
mannose receptor, C type 1
NCBI Official Symbol
Mrc1
NCBI Official Synonym Symbols
MR; CD206; AW259686
NCBI Protein Information
macrophage mannose receptor 1; MMR
UniProt Protein Name
Macrophage mannose receptor 1
UniProt Entry Name
MRC1_MOUSE
Research Articles on CD206
Similar Products
Product Notes
The CD206 (Catalog #AAA2568366) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The PE/Cyanine7 Anti-Mouse CD206 Antibody [C068C2] reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD206 can be used in a range of immunoassay formats including, but not limited to, ICFlow Cytometry (FC/FACS/FCM). Researchers should empirically determine the suitability of the CD206 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD206, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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